This report summarizes a one year evaluation of Abbott's ABA 100, with respect to mechanical parts (syringe plates, precision and linearity of photometry, band width of several filters, multicuvet precision, temperature control) and the reliability of several methods (endpoint procedures: determination of the glucose concentration with hexokinase- and the glucose dehydrogenase method, and of th...

It is argued that the dominant subleading shape-function contributions to the endpoint region of the charged-lepton energy spectrum in B → Xu l ν decays can be related in a model-independent way to an integral over the B → Xsγ photon spectrum. The square root of the fraction of B → Xu l ν events with chargedlepton energy above E0 = 2.2GeV can be calculated with a residual theoretical uncertaint...

BACKGROUND RNA extracted from formalin-fixed paraffin-embedded (FFPE) samples is chemically modified and degraded, which compromises its use in gene expression studies. Most of the current approaches for RNA quality assessment are not suitable for FFPE derived RNA. RESULTS We have developed a single-tube multiplex endpoint RT-PCR assay specifically designed to evaluate RNA extracted from FFPE...

BACKGROUND Impairment of spatiotemporal visual processing in amblyopia has been studied extensively, but its effects on visuomotor tasks have rarely been examined. Here, we investigate how visual deficits in amblyopia affect motor planning and online control of visually-guided, unconstrained reaching movements. METHODS Thirteen patients with mild amblyopia, 13 with severe amblyopia and 13 vis...

Lyophilization is widely used in the preservation of thermolabile products. The main shortcoming long processing time. processes are mostly based on a recipe that not changed, but, with Quality by Design (QbD) approach and use Process Analytical Technology (PAT), process duration can be optimized for maximum productivity while ensuring product safety. In this work, an advanced PAT endpoint dete...