نتایج جستجو برای: endocrine related cancer
تعداد نتایج: 2032507 فیلتر نتایج به سال:
introduction: the present study aimed to assess the efficacy of use of combined cognitive interventions to prepare the child and parent, and distraction of child’s attention on reported intensity of pain, distress caused by lumbar puncture, and situation-related quality of life of children with cancer. method : this was a clinical trial using pretest-posttest method and a control group. study...
intense scientific work has improved our understanding of the impacts of endocrine-disrupting chemicals (EDCs) on human and wildlife health, such that in 2012, the UNEP and WHO, in collaboration with international experts, have produced an updated document on EDCs, that includes scientific information on human and wildlife impacts and lists key concerns for decision makers and others concerned ...
BACKGROUND Concerns have been raised about the risk of dementia associated with antiestrogen adjuvant therapy in breast cancer, but study results have been inconsistent. We examined whether tamoxifen or other endocrine therapy was associated with dementia risk in a large population of patients with breast cancer. METHODS We used Danish nationwide medical registries to identify patients with b...
Resistance is an obstacle to endocrine therapy for breast cancer. We measured levels of hypoxia-inducible factor (HIF)-1α in 52 primary breast cancer patients before and after receiving neoadjuvant endocrine therapy with letrozole for at least 3 months. Pre-treatment levels of HIF-1α were associated with negative clinical outcome. Furthermore, levels of HIF-1α were increased in post-treatment r...
abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. we report an 11 years old girl who developed central hypothyroidism and acth deficiency during the chemotherapy for cns relapse of acute lymphoblastic leukemia before receiving radiotherapy. keywords: thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leuk...
Breast cancer is a hormone-dependent cancer and usually treated with endocrine therapy using aromatase inhibitors or anti-estrogens such as tamoxifen. A majority of breast cancer, however, will often fail to respond to endocrine therapy. In the present study, we explored miRNAs associated with endocrine therapy resistance in breast cancer. High-throughput miRNA sequencing was performed using RN...
In this retrospective study, the relationship between Akt activation and the efficacy of endocrine therapy for metastatic breast cancer was investigated. Thirty-six metastatic breast cancer patients, treated with endocrine therapy, were evaluated for the activation of Akt by an immunohistochemical assessment of the expression of phosphorylated Akt at Ser 473 (pAkt). The relationship between the...
1. Chairman’s Introduction 616 R.W. Blamey 2. For which tumour types should endocrine therapy be restricted? 617 R. Nicholson, W. Miller, P.E. Lonning 3. Endocrine therapy in primary breast cancer 619 L. Rutqvist, R. Jakesz, A. Goldhirsch, M. Baum 4. Endocrine therapy in primary breast cancer 624 C. Rose, F. Boccardo, M. Piccart, B.J.K. Thürlimann, K. Holli 5. Other indications for endocrine th...
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