نتایج جستجو برای: endocrine related cancer

تعداد نتایج: 2032507  

Journal: :basic and clinical cancer research 0
maryam farrokhnia shahid beheshti university, tehran, iran shahriar shahidi department of psychology and educational sciences, shahid beheshti university, tehran, iran jalil fathabadi department of psychology and educational sciences, shahid beheshti university, tehran, iran

introduction: the present study aimed to assess the efficacy of use of combined cognitive interventions to prepare the child and parent, and distraction of child’s attention on reported intensity of pain, distress caused by lumbar puncture, and situation-related quality of life of children with cancer. method : this was a clinical trial using pretest-posttest method and a control group. study...

2013
Åke Bergman Jerrold J. Heindel Tim Kasten Karen A. Kidd Susan Jobling Maria Neira R. Thomas Zoeller Georg Becher Poul Bjerregaard Riana Bornman Ingvar Brandt Andreas Kortenkamp Derek Muir Marie-Noël Brune Drisse Roseline Ochieng Niels E. Skakkebaek Agneta Sundén Byléhn Taisen Iguchi Jorma Toppari Tracey J. Woodruff

intense scientific work has improved our understanding of the impacts of endocrine-disrupting chemicals (EDCs) on human and wildlife health, such that in 2012, the UNEP and WHO, in collaboration with international experts, have produced an updated document on EDCs, that includes scientific information on human and wildlife impacts and lists key concerns for decision makers and others concerned ...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2013
Anne Gulbech Ording Anders Bonde Jensen Deirdre Cronin-Fenton Lars Pedersen Henrik Toft Sørensen Timothy L Lash

BACKGROUND Concerns have been raised about the risk of dementia associated with antiestrogen adjuvant therapy in breast cancer, but study results have been inconsistent. We examined whether tamoxifen or other endocrine therapy was associated with dementia risk in a large population of patients with breast cancer. METHODS We used Danish nationwide medical registries to identify patients with b...

2015
Xiaoqing Jia Qi Hong Li Lei Daqiang Li Jianwei Li Miao Mo Yujie Wang Zhimin Shao Zhenzhou Shen Jingyi Cheng Guangyu Liu

Resistance is an obstacle to endocrine therapy for breast cancer. We measured levels of hypoxia-inducible factor (HIF)-1α in 52 primary breast cancer patients before and after receiving neoadjuvant endocrine therapy with letrozole for at least 3 months. Pre-treatment levels of HIF-1α were associated with negative clinical outcome. Furthermore, levels of HIF-1α were increased in post-treatment r...

Journal: :iranian journal of blood and cancer 0
ansari sh rostami t kiumarsi a

abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. we report an 11 years old girl who developed central hypothyroidism and acth deficiency during the chemotherapy for cns relapse of acute lymphoblastic leukemia before receiving radiotherapy. keywords: thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leuk...

2015
Kazuhiro Ikeda Kuniko Horie-Inoue Toshihide Ueno Takashi Suzuki Wataru Sato Takashi Shigekawa Akihiko Osaki Toshiaki Saeki Eugene Berezikov Hiroyuki Mano Satoshi Inoue

Breast cancer is a hormone-dependent cancer and usually treated with endocrine therapy using aromatase inhibitors or anti-estrogens such as tamoxifen. A majority of breast cancer, however, will often fail to respond to endocrine therapy. In the present study, we explored miRNAs associated with endocrine therapy resistance in breast cancer. High-throughput miRNA sequencing was performed using RN...

Journal: :European journal of cancer 2006
Eriko Tokunaga Akemi Kataoka Yasue Kimura Eiji Oki Kojiro Mashino Kojiro Nishida Tadashi Koga Masaru Morita Yoshihiro Kakeji Hideo Baba Shinji Ohno Yoshihiko Maehara

In this retrospective study, the relationship between Akt activation and the efficacy of endocrine therapy for metastatic breast cancer was investigated. Thirty-six metastatic breast cancer patients, treated with endocrine therapy, were evaluated for the activation of Akt by an immunohistochemical assessment of the expression of phosphorylated Akt at Ser 473 (pAkt). The relationship between the...

Journal: :European journal of cancer 2002
R W Blamey

1. Chairman’s Introduction 616 R.W. Blamey 2. For which tumour types should endocrine therapy be restricted? 617 R. Nicholson, W. Miller, P.E. Lonning 3. Endocrine therapy in primary breast cancer 619 L. Rutqvist, R. Jakesz, A. Goldhirsch, M. Baum 4. Endocrine therapy in primary breast cancer 624 C. Rose, F. Boccardo, M. Piccart, B.J.K. Thürlimann, K. Holli 5. Other indications for endocrine th...

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