Due to the complexity of biological tissue and variations in staining procedures, features that are based on the explicit extraction of properties from subglandular structures in tissue images may have difficulty generalizing well over an unrestricted set of images and staining variations. We circumvent this problem by an implicit representation that is both robust and highly descriptive, espec...

The ever increasing rate at which whole genome sequences are becoming accessible to the scientific community has created an urgent need for tools enabling comparison of chromosomes of different species. We have applied biometric methods to available chromosome sequences and posted the results on our Comparative Genometrics (CG) web site. By genometrics, a term coined by Elston and Wilson [GENET...

Abstract. Between 14 and 20 July 2018, small remotely piloted aircraft systems (RPASs) were deployed to the San Luis Valley of Colorado (USA) together with a variety surface-based remote in situ sensors as well radiosonde part Lower Atmospheric Profiling Studies at Elevation – Remotely-piloted Aircraft Team Experiment (LAPSE-RATE). The observations from LAPSE-RATE aimed improving our understand...

The McCarron-Dial System (MDS) was developed as an empirically based, multifactor assessment battery. Originally introduced to the field of rehabilitation as a vocational evaluation tool, its use has been expanded to include applications in virtually all areas of neurocognitive assessment and treatment (Chan, et al., 1993; Botterbusch, 1982). Expansion of the MDS was necessary to meet the conti...

We presented a risk assessment model to distinguish between type 1 diabetes (T1D) affected and unaffected siblings using only three single nucleotide polymorphism (SNP) genotypes. In addition we calculated the heritability from genome-wide identity-by-descent (IBD) sharing between full siblings. We analyzed 1,253 pairs of affected individuals and their unaffected siblings (750 pairs from a disc...

To test for genetic association between a marker and a complex disease using a case-control design, Cochran-Armitage trend tests (CATTs) and Pearson's chi-square test are often employed. Both tests are genotype-based. Song and Elston (Statist. Med. 2006; 25:105-126) introduced the Hardy-Weinberg disequilibrium trend test and combined it with CATT to test for association. Compared to using a sin...

OBJECTIVE To identify genetic loci that control intraocular pressure (IOP). METHODS We performed a genomewide scan of IOP, using 486 pedigrees ascertained through a population-based cohort, the Beaver Dam Eye Study. Linkage analysis was performed using the modified Haseman-Elston regression models and variance components linkage analysis. RESULTS Seven regions of interest were identified on...

CA15-3 is a high-molecular-mass mucin-like glycoprotein expres¬sed at the luminal surface of most secretary epithelia and associated with mammary tumors (Taylor et al., 2002). Increased levels were observed in patients with breast cancer (Kobayashi et al., 1989). Clinical uses of this marker include monitoring of patients with breast cancer (Duffy, 1999; Duffy et al., 2006), prognosis (McLaughl...

Fine needle aspiration biopsy of breast lump is an accepted and established method to determine the nature of lump and it may play an important role when it is difficult to determine the nature of the breast lump by clinical examination. It has been shown that FNAB can reduce number of open breast biopsies. Study was done to assess utility of FNAC as the initial diagnostic tool in patients with...

The following synonymies are proposed based on examination of primary types (lectotypes are designated for all taxa except those marked with a '*'): Lemidia spinnipennis Lea, 1907 syn. n. and Lemidia bicolor Schenkling, 1906 syn. n. = Lemidia biaculeata (Westwood); Lemidia mastersi Lea, 1907 syn. n. = Lemidia circumcincta Schenkling, 1906; Lemidia albonotata Pic, 1941 syn. n. = Lemidia laticeps...