نتایج جستجو برای: derived cephalosporinase

تعداد نتایج: 481974  

Journal: :European Journal of Medicinal Chemistry 2021

The occurrence of resistances in Gram negative bacteria is steadily increasing to reach extremely worrying levels and one the main causes resistance massive spread very efficient ?-lactamases which render most ?-lactam antibiotics useless. Herein, we report development a series imino-analogues ?-lactams (namely azetidinimines) as non-covalent inhibitors ?-lactamases. Despite structural mechanis...

Journal: :Antimicrobial agents and chemotherapy 1985
K Murakami T Yoshida

The inhibition of Citrobacter freundii cephalosporinase activity by moxalactam is shown to be due to the formation of a transiently stable covalent complex, probably acyl enzyme. The covalent complex formed was identified by coelution of [14C] moxalactam with the enzyme by using Sephadex G-25 gel filtration in the presence of 5.7 M guanidine hydrochloride and by analytical isoelectric focusing....

Journal: :Journal of general microbiology 1965
G A Ayliffe

Journal: :Journal of clinical microbiology 2012
Rene S Hendriksen Simon Le Hello Valeria Bortolaia Chaiwat Pulsrikarn Eva Møller Nielsen Srirat Pornruangmong Phattharaporn Chaichana Christina Aaby Svendsen François-Xavier Weill Frank M Aarestrup

Salmonella enterica serovar Stanley (S. Stanley) is a common serovar in Southeast Asia and was the second most common serovar implicated in human salmonellosis in Thailand in the years 2002 to 2007. In contrast, this serovar is relatively uncommon in Europe. The objective of this study was to characterize a collection of S. Stanley strains isolated from Thai (n = 62), Danish (n = 39), and Frenc...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی اصفهان 1371

the effect of the presence of perforations on he stresses of a plate is a problem which is of great interest in structural design and in the mathemattical theory of elasticity. among the many hole patterns that are likely to require consideration is the ring of equally spaced circular holes. the present worke investigates stress & strain analysis of a thin isotropic circular plate containing a ...

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