نتایج جستجو برای: cytochrome

تعداد نتایج: 50088  

2015
Alexandr N. Simonov Jessica K. Holien Joyee Chun In Yeung Ann D. Nguyen C. Jo Corbin Jie Zheng Vladimir L. Kuznetsov Richard J. Auchus Alan J. Conley Alan M. Bond Michael W. Parker Raymond J. Rodgers Lisandra L. Martin Hang Hubert Yin

Cytochrome P450c17 (P450 17A1, CYP17A1) is a critical enzyme in the synthesis of androgens and is now a target enzyme for the treatment of prostate cancer. Cytochrome P450c17 can exhibit either one or two physiological enzymatic activities differentially regulated by cytochrome b5. How this is achieved remains unknown. Here, comprehensive in silico, in vivo and in vitro analyses were undertaken...

Journal: :Journal of bacteriology 1970
A Domnas N G Grant

The cytochrome composition of 19 strains of Actinoplanaceae has been investigated. The principal cytochrome found was cytochrome b, and occasional strains showed the presence of cytochrome a.

Mycophenolic acid (MPA) is the active metabolite of mycophenolate mofetil. This study designed to investigate the mechanism of cytotoxicity of MPA on the genetically engineered PC12 Tet Off (PTO) neuronal cells with p53 gene. Alamar Blue (AB) reduction showed concentration-dependent cytotoxicity of MPA on PTO cells with IC50 value of 32.32 ± 4.61 mM. The reactive oxygen species (ROS) generation...

The effect of Annona squamosa, Lawsonia inermis and their combination with other herbal molluscicides were studied on different enzyme activity in the nervous tissue of Lymnaea acuminata. Twenty-Four hour in vivo exposure to 40% and 80% of 24 h LC50 of plant derived molluscicides and their combination with other molluscicides such as Cedrus deodara, Azadirachta indica oil, Allium sativum, Polia...

Journal: :The Biochemical journal 1980
P M Wood

Photosynthetic electron flow in the bacterium Rhodopseudomonas sphaeroides involves two c-type cytochromes, one membrane-bound and the other a soluble protein, cytochrome c2. Membranes deficient in cytochrome c2 were used for photo-oxidation studies, with and without the addition of purified cytochrome c2. The results favour a series interrelation, membrane cytochrome c-cytochrome c2-reaction c...

Journal: :iranian journal of microbiology 0
shirin sadr davood darban-sarokhalil gholam reza irajian abbas ali imani fooladi jaleh moradi mohammad mehdi feizabadi

background and objectives: for further confirmation of the previous in-house real-time pcr and cyp 141 target as a rapid and cheap diagnostic technique and a new target for direct detection of mycobacterium tuberculosis , we evaluated and compared the results of smear, culture and real-time pcr in sputa that were collected from 2 health centers. moreover we tried to evaluate the diagnostic accu...

Journal: :iranian journal of public health 0
b khoshpey school of public health, tehran university of medical sciences, tehran, iran dd farhud school of public health, tehran university of medical sciences, tehran, iran f zaini school of public health, tehran university of medical sciences, tehran, iran

many studies have shown that mycotoxin contamination of agricultural products is a challenge for individual's health espe­cially in developing countries. improper production and storage of foods, prepare conditions for aflatoxin production in crops, especially rice, wheat, pistachio, walnut, almond, etc which are the main sources of foods for people. feeding live­stock by contaminated bread is ...

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