PURPOSE To investigate the genetic diversity of toxigenic Clostridium strains isolated from soil, water, meat and its associated polluted sites of Southern India. MATERIALS AND METHODS A total of 27 identified isolates of six different toxigenic clostridial species including C. bifermentans , C. botulinum , C. chauvoei , C. ramosum , C. tetani and C. novyi were isolated and characterized by c...

Nishida, Shoki (Kanazawa University, Kanazawa, Japan), and Gizo Nakagawara. Relationship between toxigenicity and sporulating potency of Clostridium novyi. J. Bacteriol. 89:993-995. 1965.-The less toxigenic the strains, the stronger was the sporulating potency of Clostridium novyi strains isolated. This was confirmed by investigation of the toxigenicity of substrains of C. novyi 140 possessing ...

Here, we report the genome sequence of a rare bivalent strain of Clostridium botulinum, A2B3 87. The strain was isolated from a foodborne botulism case that occurred in Italy in 1995. The case was characterized by rapid evolution of the illness and failure of conventional treatments.

Low-level vancomycin resistance was observed for 28 clinical Clostridium innocuum isolates and C. innocuum NCIB 10674, whereas teicoplanin was active. DNA from three clinical isolates and the type strain could not be amplified by PCR with primers specific for the genes vanA, vanB, and vanC, suggesting that C. innocuum is intrinsically resistant to vancomycin.

In a study to identify the clostridial species associated with sporadic diarrhoea in children aged 5 years and below, clostridia species were isolated from 57 (3%) of 1761 diarrhoeic faecal samples studied. Fifty-one of the clostridial isolates were identified as Clostridium perfringens while the other six isolates were identified as C. bifermentans. Forthy-seven were C. perfringens type A, 4 w...

Sixty-two isolates of Clostridium sporogenes from canned foods were examined for cultural properties, heat resistance and DNA-DNA homology to Clostridium botulinum type A190. Sporulation was observed in most of 21 umbonate and rhizoidal colony-forming strains (colony-type I strains), but not in most of the 41 strains with convex and circular or crenate colonies with a mat to semi-glossy surface...

tetanus is an important disease which created by tetanospasmin toxin of clostridium tetani. in this study we surveyed six important factors including lf, kf, mld, ph, od and total protein assay of harvard 52 (h52), g5 (hg5) and 49205 (h49205) strains of the bacterium to determine which of them were more suitable for use in vaccine production. the mentioned strains were seperatedly reactivated i...

introduction: toxigenic clostridium difficile is the major cause of antibiotic-associated diarrhea, colitis, and pseudomembranous colitis. the pathogenicity of c. difficile is related to toxins a&b.; children with cancer are at risk of developing c. difficile infection (cdi) due to increased exposure to antibiotics, immunosuppression, and longer hospital stays. recently, due to higher sensitivit...