BACKGROUND A significant number of pregnancies are associated with the cytogenetic abnormalities of the fetus. Amniocentesis and chorionic villus sampling (CVS) are procedures used for prenatal genetic diagnosis. In this study, we compare the safety and complications of mid-trimester amniocentesis and transabdominal CVS. MATERIALS AND METHODS This analytic cross-sectional study was performed ...

OBJECTIVE To examine the possible association between high fetal nuchal translucency thickness (NT) and pathogenic chromosomal copy number variants (CNVs) detected by array comparative genomic hybridization (CGH) in pregnancies with normal fetal karyotype. METHODS Array CGH was carried out in stored samples of chorionic villi from 215 singleton pregnancies resulting in live births in which ch...

Background: Hydatidiform mole is a gestational trophoblastic disease with the highest incidence in Indonesia where 1 40 pregnancies. The cause of high influenced by reproductive performance patients such as disorders hypothalamic-pituitary-ovarian system which causes hyperproliferation cells, hydrophic degeneration chorionic villi, and increased levels β-hCG. Methods: This research was involvin...

The nuclear factor kappa B is widely expressed in the distinct subpopulations of chorionic villi and deciduas of first-trimester pregnancies. We examined the cellular distribution and expression of nuclear factor kappa B in the human first-trimester chorionic villi and deciduas of women with early spontaneous miscarriage and viable pregnancy by confocal laser scanning microscope and immunohisto...

Background: Placental transmogrification of the lung is a very rare benign disease with characteristic finding being alveoli resembling chorionic villi placenta. The purpose this study was to assess computed tomography (CT) findings placental in six patients and their relation histopathologic findings.

OBJECTIVE To determine the ultrastructural changes of the placenta in women with pre-eclampsia and eclampsia compared to the placenta of normotensive patients. STUDY DESIGN Comparative descriptive study. PLACE AND DURATION OF STUDY Obstetrics Unit of North Colombo Teaching Hospital, Ragama, Sri Lanka in 2004. METHODOLOGY Placentae of 10 normotensive women and 10 hypertensive women with pr...

Placenta accreta occurs when the deciduas basal is that separates the placental villi from the myometrium is missing. Classification is divided in 3 grades based on histopathologic analysis consisting on: placenta accreta, increate and percent. Placenta accreta occurs when the chorionic villi of the placenta enters in contact with the myometrium. In placenta increta, the chorionic villi invade ...

objective(s):to determine the fetal discernment in suspected cases of sex linked recessive disease in the first trimester of pregnancy. materials and methods: after collection of 100 chorionic villi samples, the dnas were extracted and baby gender was determined. meanwhile, after increasing the sensitivity, the system was able to detect the sex of each cell which was obtained by biopsy. results...