transcranial current stimulation (tcs) is a neuromodulation method in which the patient is exposed to a mild electric current (direct or alternating) at 1-2 ma, resulting in an increase or a decrease in the brain excitability. this modi.cation in neural activities can be used as a method for functional human brain mapping with causal inferences. this method might also facilitate the treatments ...

To determine if anodal excitation during bipolar stimulation facilitates the initiation of sustained monomorphic ventricular tachycardia, nonsustained polymorphic ventricular tachycardia, or repetitive ventricular responses, both bipolar and cathodal unipolar programmed ventricular stimulation with one to three extrastimuli delivered during ventricular pacing at two rates from the right ventric...

BACKGROUND Cathodal transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation method for suppressing regional cortical excitability. We examine the safety and antiepileptic efficacy of cathodal tDCS in children with refractory focal epilepsy. Although a prior cathodal tDCS trial in adults with epilepsy revealed EEG improvement, neither the antiepileptic potential nor the...

BACKGROUND AND PURPOSE Transcranial direct current stimulation is emerging as a promising tool for the treatment of several neurological conditions, including cerebral ischemia. The therapeutic role of this noninvasive treatment is, however, limited to chronic phases of stroke. We thus ought to investigate whether different stimulation protocols could also be beneficial in the acute phase of ex...

OBJECTIVE Invasive stimulation of the motor cortex has been used for years to alleviate chronic intractable pain in humans. In our study, we have investigated the effect of transcranial direct current stimulation (tDCS), a noninvasive stimulation method, for manipulating the excitability of cortical motor areas on laser evoked potentials (LEP) and acute pain perception. DESIGNS AND SETTINGS: Th...

Focal hand dystonia (FHD) in musicians is a movement disorder causing abnormal movements and irregularities in playing. Since weak electrical currents applied to the brain induce persistent excitability changes in humans, cathodal tDCS was proposed as a possible non-invasive approach for modulating cortical excitability in patients with FHD. However, the optimal targets and modalities have stil...

OBJECTIVES : The use of noninvasive cortical electrical stimulation with weak currents has significantly increased in basic and clinical human studies. Initial, preliminary studies with this technique have shown encouraging results; however, the safety and tolerability of this method of brain stimulation have not been sufficiently explored yet. The purpose of our study was to assess the effects...

previous studies have shown that electrical stimulation (es) increases blood flow, but the exact mechanisms are not clear. the present study was designed to clarify some of the underlying mechanisms involved in this phenomenon. white adult rabbits lt.-6 months old were used. animals were anesthetized by sodium pentobarbital (40 mg/kg, iv) and skin blood flow in the thoracic back was recorded us...

introduction: although hippocampus is the most famous brain area involved in temporal lobe epilepsy, hippocampal kindling (hk) develops very slowly. hence, rapid kindling is usually preferred to the traditional kindling and it is widely used. in this article we aimed at finding the optimal stimulus pattern, which yields the fastest hk rate. methods: stimulus patterns with different duration (2,...