Introduction: Nowadays, several casein components such as casein phosphopeptide amorphous calcium phosphate (CPP-ACP) are vastly considered as a suitable replacement for fluoride component. The aim of this study was to compare the effect of CPP-ACP paste and fluoride varnish on dentin hypersensitivity reduction. Materials & Methods: In this clinical trial study, thirty adult patients between th...

Introduction: Dentin hypersensitivity is a pain arising from exposed dentin, typically in response to clinical, thermal, tactile, evaporative or osmotic stimuli that cannot be explained as arising from any other form of dental pathology. Most authorities agree that Brannstrom’s “Hydrodynamic Theory" of nerve stimulation due to movement of dentinal fluid, best explains dentin hypersensitivity. T...

Objective: One complication of fixed orthodontic treatment in patients with poor oral hygiene is development of demineralized enamel lesions compromising esthetics. This study aimed to review preventive measures and treatment of white spot lesions (WSLs) in patients with fixed orthodontic appliances. Review of Literature: In this review study, PubMed and Google Scholar databases were searched f...

BACKGROUND The aim of study was to evaluate the application of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride regarding their effect on the shear bond strength (SBS), bond failure pattern of brackets using the adhesive remnant index (ARI) and assessing the quality of enamel surface using the enamel damage index (EDI). MATERIAL AND METHODS Sixty extracted premolar tee...

AIM This review of the literature examines the role of the natural components of saliva in maintaining tooth mineralization and the role of different casein phosphopeptide amorphous calcium phosphate-based (CPP-ACP) compounds in controlling demineralization/remineralization and their clinical applications. BACKGROUND A group of peptides, known as CPP, have been shown to stabilize calcium and ...

The dishevelled (dsh) gene of Drosophila melanogaster encodes a phosphoprotein whose phosphorylation state is elevated by Wingless stimulation, suggesting that the phosphorylation of Dsh and the kinase(s) responsible for this phosphorylation are integral parts of the Wg signaling pathway. We found that immunoprecipitated Dsh protein from embryos and from cells in tissue culture is associated wi...

This study aimed to examine the anti-demineralization capacities of (a) tetracalcium phosphate (TTCP) and dicalcium phosphate anhydrous (DCPA) and 950 ppm fluoride paste, (b) casein phosphopeptide amorphous calcium phosphate paste and (c) 950 ppm fluoride solution using optical coherence tomography (OCT). Enamel blocks were cut from the bovine incisors and treated using one of the above-mention...

BACKGROUND CPP-ACP (Phosphopeptide-Amorphous Calcium Phosphate) has an important role in caries prevention in pediatric patients. This study was done, because of the great use of CPP-ACP and the need for restoration for teeth treated with CPP-ACP as well as the importance of shear bond strength of adhesives in the success of restorations. OBJECTIVES This study aimed to evaluate the effect of ...

BACKGROUND The aim of this study was to assess the effect of Nd:YAG laser irradiation following casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) application on calcium and phosphate concentration and surface microhardness (SMH) of enamel surface in artificial white spot lesions of primary teeth. MATERIAL AND METHODS Eighty teeth with artificial white spot lesions were randomly divi...

AIM Casein phosphopeptide stabilised amorphous calcium phosphate (CPP-ACP) has been shown to remineralise enamel subsurface lesions. The aim of this study was to determine the effect of a paste containing 10% CPP-ACP (Toothmousse; GC) on enamel surface microhardness in vitro. MATERIALS AND METHODS Thirty enamel blocks (3x2 mm) were prepared for the study group from the buccal surface of ex...