The protein tyrosine kinase expressed by the protooncogene c-fgr is phosphorylated and down-regulated in vitro by the c-Src kinase (CSK). CSK catalyzed phosphorylation affects Tyr-511 of c-Fgr, homologous to Tyr-527 of c-Src and it prevents the autophosphorylation normally occurring at c-Fgr Tyr-400, homologous to c-Src Tyr-416. Polylysine, histones H1 and H2A and other polycationic proteins on...

Performance prediction of checkpointing systems in the presence of failures is a well-studied research area. This paper makes three small contributions to this research area. First, we show how to apply the concept of availability from reliability theory as a useful metric for checkpointing systems. Second, we study the average availability of uniprocessor checkpointing systems, using the libck...

Patients with impaired immunity are at particular risk of infections with Candida albicans. Antifungal drugs such as azoles commonly used for candidiasis treatment, but drug resistance is one of the most common problems for public health. The aim of this study was to evaluate the expression of lanosterol 14-demethylase (ERG11) gene for three-drug combinations in C. albicans. Disk diffusion and ...

On arithmetic and asymptotic properties of up-down numbers. We prove that the set of all up-down numbers C(σ) can be expressed by a single universal polynomial Φ, whose coefficients are products of numbers from the Taylor series of the hyperbolic tangent function. We prove that Φ is a modified exponential, and deduce some remarkable congruence properties for the set of all numbers C(σ), for fix...