Bioinformatics and computational biology are up-and-coming disciplines that have recently made waves in technological fields and in the media. They’re two of the few fields that require a wide spectrum of knowledge, from biology to computing and everything in between. Wikipedia defines bioinformatics as involving “the use of techniques from applied mathematics, informatics, statistics, computer...

Pål O. Westermark, Jeanette Hellgren Kotaleski, Anneli Björklund, Valdemar Grill, and Anders Lansner Parallel Scientific Computing Institute/Computational Biology and Neurocomputing, Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden; Institute for Theoretical Biology, Humboldt University Berlin, Berlin, Germany; Department of Molecular Medicine, Endocrine and ...

Update of molecular biology databases is a growing burden on the biomedical research community. As the grid allows to share and replicate data, we propose a service to automatically update the biology databases from a single changing reference using web services. In this paper we report the components, the architecture and the deployment of the update service on the french RUGBI grid infrastruc...

In this paper we discuss metaphores inspired by structural biology, genetics, neurology and immunology for building complex software systems. Structural biology offers hints for software composition. Genetics provides ideas to construct software modules from descriptions. A network of software agents could emulate the nervous system, coordinate various activities and mediate amongst interacting...

radically different computing concepts that leverage the physics of biological materials. For example, selforganization, self-repair, and self-reproduction are commonly found in biological systems but are difficult to achieve with conventional computing systems. New computing paradigms, such as cellular automata, neural networks, and evolutionary computing, may provide clues to utilize the comp...

1 Computational Molecular Biology Department, Max Planck Institute for Molecular Genetics, Ihnestr. 73, 14195 Berlin, Germany, 2 International Max Planck Research School for Computational Biology and Scientific Computing, Berlin, Germany, and 3 Institute of Informatics, Warsaw University, Banacha 2, 02-097, Warsaw, Poland 4 Present address: Broad Institute of MIT and Harvard, 7 Cambridge Center...

Since the earliest days of the electronic computer, there has always been a small group of people who have seen the computer as an extension of biology, and have endeavored to build computing models and even hardware that are inspired by, and in some cases, direct copies of biological systems. Though biology spans a wide range of systems, the primary model for these early efforts has been neura...

1 Laboratory of Brain Imaging, Neurobiology Centre, Nencki Institute of Experimental Biology, Warsaw, Poland 2 Laboratory of Psychophysiology, Department of Neurophysiology, Nencki Institute of Experimental Biology, Warsaw, Poland 3 University of Social Sciences and Humanities, Warsaw, Poland 4 Faculty of Psychology, University of Warsaw, Warsaw, Poland 5 Faculty of Electrical Engineering and C...

In this paper we discuss metaphores inspired by structural biology, genetics, neurology and immunology for building complex software systems. Structural biology offers hints for software composition. Genetics provides ideas to construct software modules from descriptions. A network of software agents could emulate the nervous system, coordinate various activities and mediate amongst interacting...

Molecular biology has posed a number of fascinating and sometimes daunting computational problems, which came naturally expressed in its native language of character strings. Through the years, some such problems have found elegant and even useful solutions in response to the needs that originally motivated them. What is perhaps even more remarkable, several of the ideas inspired by computation...