Staphylococcus aureus (S. aureus) is the most common pathogen causing infections from skin to systemic infections. The success of S. can partially be attributed its antibiotic resistance and ability form biofilm. An increasing prevalence methicillin-resistant (MRSA) becomes a global public health problem in recent decades. Here, effects tea catechin extracts on growth biofilm formation three MR...

The chemical composition of propolis varies according to factors that could have an influence on its biological properties. Polyphenols from propolis have demonstrated an inhibitory effect on Streptococcus mutans growth. However, it is not known if different years of propolis collection may affect its activity. We aimed to elucidate if the year of collection of propolis influences its activity ...

Prostaglandins are now known to be produced by Candida albicans and may play an important role in fungal colonization. Their synthesis in mammalian cells is decreased by inhibitors of the cyclooxygenase isoenzymes required for prostaglandin formation. In the present study, a catheter disk model system was used to investigate the effects of nonsteroidal anti-inflammatory drugs (all cyclooxygenas...

HIGHLIGHTS Essential oil (EO) of Niaouli is an inhibitor on biofilm formation P. aeruginosa. The main components EO act as possible inhibitors LasR. inhibition effect these molecules LasR verified by molecular docking. has effects cell viability fibroblast cells at high concentrations. a valuable essential for pharmaceutical applications.

OBJECTIVES To evaluate the inhibitory effect of ursolic acid (UA)-containing composites on Streptococcus mutans (S. mutans) biofilm. MATERIALS AND METHODS Composite resins with five different concentrations (0.04, 0.1, 0.2, 0.5, and 1.0 wt%) of UA (U6753, Sigma Aldrich) were prepared, and their flexural strengths were measured according to ISO 4049. To evaluate the effect of carbohydrate sour...

ECCMID08_R2330: Contact View [R2330] Effect of farnesol on planktonic versus biofilm cells of Staphylococcus epidermidis F.I. Gomes, R. Oliveira, P. Teixeira. (Braga, PT) Objectives: Staphylococcus epidermidis is the most frequent cause of nosocomial sepsis and catheterrelated infections, in which biofilm formation is considered to be the main virulence mechanism. Quorumsensing system have been...

The present work was performed to determine the impacts of commercial disinfectants against biomass, viability, and biochemical composition Salmonella enterica serovar Thyphimurium ATCC14028 biofilm. biofilm grown in microplates exposed namely sodium hypochlorite, benzalkonium chloride, chloroxylenol, dodecyl-benzene sulfonate-based disinfectants. Biofilm were determined using crystal violet as...

AIMS Polysaccharide intercellular adhesin (PIA) is the main agglutination agent in the biofilm forming strain Staphylococcus epidermidis. To find an explanation for the observed inhibition of biofilm formation by allicin, we studied the effect of allicin on PIA production in samples treated with sub MIC doses of allicin and compared this with a control culture without allicin. METHODS AND RES...

The natural compound zosteric acid, or p-(sulfoxy)cinnamic acid (ZA), is proposed as an alternative biocide-free agent suitable for preventive or integrative anti-biofilm approaches. Despite its potential, the lack of information concerning the structural and molecular mechanism of action involved in its anti-biofilm activity has limited efforts to generate more potent anti-biofilm strategies. ...

The natural compound zosteric acid, or p-(sulfoxy)cinnamic acid (ZA), is proposed as an alternative biocide-free agent suitable for preventive or integrative anti-biofilm approaches. Despite its potential, the lack of information concerning the structural and molecular mechanism of action involved in its anti-biofilm activity has limited efforts to generate more potent anti-biofilm strategies. ...