in order to prepare polyurethane elastomers with acceptable physical properties and good biocompatibility, novel polyurethane networks were synthesized via curing reaction of epoxy-terminated polyurethane prepolymers (eups) with hexamethylene diamine. eups were prepared from reaction of glycidol with nco-terminated polyurethanes (itps). itps were also synthesized from reaction of one equivalent...

The surface is of critical importance in determining the in vivo performance and acceptance of an implant, with respect to both tissue and blood. Material surface properties have been studied intensively, but only in recent years have quantitative, mechanistic links been made to biomolecular and cellular interactions driven by the surface. This review focuses mainly on polymeric surfaces both b...

Polymeric biomaterials are being widely used for the treatment of various traumata, diseases and defects in human beings due to ease in their synthesis. As biomaterials have direct interaction with the extracellular environment in the biological world, biocompatibility is a topic of great significance. The introduction or enhancement of biocompatibility in certain polymers is still a challenge ...

BACKGROUND A new treatment strategy is to target specific areas of the skeletal system that are prone to clinically significant osteoporotic fractures. We term this strategy as the "local treatment of osteoporosis". The study was performed to investigate the effect of alendronate-loaded calcium phosphate cement (CPC) as a novel drug delivery system for local treatment of osteoorosis. METHODS ...