Background and Aim: Atherosclerosis is known as a multifactorial inflammatory disease. Trimethylamine N-oxide (TMAO) as a risk factor, has a potential to trigger or enhance the immune inflammatory reactions in atherosclerosis. Yet, The exact mechanism by which TMAO induces inflammation during atherosclerosis is not well understood. The present study was designed to evaluate the expression of IL...

Osteopontin also known as bone sialoprotein (BSP). Osteopontin role as a linking protein. it is an extracellular structural protein and therefore an organic component of bone. Osteoprontin (OPN) binds to several integrin receptors containing α4β1, α9β1, and α9β4 expressed by leukocytes. These receptors have been well-stable to function in cell adhesion, migratio...

introduction: using beta emitter radionuclide is a useful therapeutic modality in the treatment of skin cancers in areas which are difficult to cure by other methods. the aim of this research is to evaluate the tissue response to beta rays of 166ho and determine the feasibility of beta emitting radionuclide for treatment of skin cancers. methods: in this work, we have calculated depth dose dist...

The selective activity of an antineoplastic drug is related to its ability promote cytotoxic action on tumor cells and preserve the integrity non-neoplastic cells. Beta-lapachone extracted from sawdust Ipe wood, a thick bark tree wood found in Brazilian Cerrado biome. This study aimed evaluate beta-lapachone endothelial cell line. EA.hy926 were seeded two groups, G1 G2, cultured exposed at conc...

Background: Adipose-derived stem cells (ADSCs) are a population of pluripotent cells used for tissue engineering purposes. The main purpose of the present study was to transdifferentiate the ADSCs to Schwann-like cells and to determine the intensity of apoptosis in ADSCs during the transdifferentiation process. Methods: ADSCs were isolated from the inguinal adipose tissue of adult rats and the ...

proper conditions for producing crude beta-galactosidase from waste materials were de-termined. this enzyme is to be used in the production of lactose-hydrolyzed milk. whey permeate was used as a basic medium. twenty seven treatments were developed by 3 vary-ing factors of: yeast extract (1, 2, and 3 %), wheat steep liquor (1, 2, and 3 %), and whey powder (0.5, 1, and 1.5 %). crude enzyme extra...