BACKGROUND Psoas abscess complicating tuberculous spondylitis is a rare morbidity in extrapulmonary tuberculosis. There are no established guidelines for evaluating the clinical response of psoas abscess. Although several studies have shown that positron emission tomography-computed tomography with 18 F-fluorodeoxyglucose can play a potential role in diagnosing multifocal tuberculosis and monit...

epilepsy is the most frequnt nearological affiction and afflicts 1% about of the worlds population. currently there is an urgent need for the development of novel anticonvulsants with higher levels of potency and lower levels of toxicity. in this paper, a series of new 6-(substituted-phenyl)thiazolo[3,2-b][1,2,4]triazole derivatives were synthesized and tested for their anticonvulsant activity ...

in iranian traditional medicine, there are some report regarding the anticonvulsant effect of ferula gummosa boiss. in this study, anticonvulsant activity, neurological deficits and lethality of the root acetone extract of this plant were evaluated in mice. the extract exhibited dose-dependent prevention of tonic seizures induced by pentylenetetrazole (ed50 = 154.4 mg/kg). however, the extract ...

the only anticonvulsant labeled for the treatment of both postherpetic neuralgia and diabetic peripheral neuropathy. Valproic acid and topiramate are approved for the prevention of migraine headaches. Phenytoin is not frequently used to treat neuropathic pain due to its narrow therapeutic range, adverse effects and lack of demonstrated efficacy. In general, anecdotal reports have suggested that...

1,3,4-thiadiazole is one of the most potent heterocyclic containing carbonic anhydrase and antibacterial inhibitor from the natural and synthetic origin. It possessed potent anticonvulsant activity in wide range preclinical in vitro and in vivo models. Recently, various 1,3,4-thiadiazole derivatives have been synthesized and evaluated their anticonvulsant activity. This review is a demonstratio...

PURPOSE To review the clinical and radiological features and treatment outcome in 22 children who underwent one-year antitubercular multidrug treatment for tuberculosis of the cervical spine. METHODS Records of 13 boys and 9 girls aged 2 to 12 (mean, 9.1) years who underwent one-year antitubercular multidrug treatment for tuberculosis of the cervical spine were reviewed. Tuberculosis involved...