BACKGROUND The aim of this study was to evaluate the hypoglycemic, hypolipidemic, and anti-inflammatory potentials of ethanolic extract of leaves of Amaranthus paniculatus linn. (EEAP) on alloxan-induced diabetic rats scientifically. Hyperglycemia induces the generation of free radicals which can affect antioxidant defenses, thus leading to the disruption of beta cellular functions, oxidative d...

Garlic (Allium sativum L., Alliaceae), Persian shallot (Allium ascalonicum L., Alliaceae ) and Sage (Salvia officinalis L., Lamiaceae) are believed to have hypoglycemic properties and have been used traditionally as antidiabetic herbal medicines in Iran. In this study, diabetes was induced by subcutaneous injection of alloxan monohydrate (100 mg kg(-1)) to male Wistar rats. Antidiabetic effects...

Pterocarpus marsupium Roxb (Fabaceae) is a well known medicinal plant and is used in various human ailments. The ethanol extracts of Pterocarpus marsupium wood, bark and combined extract of wood and bark were investigated for its antidiabetic effect in Wistar albino rats. Diabetes was induced in Albino rats by administration of alloxan monohydrate (150mg/kg,i.p). The ethanol extracts of Pteroca...

OBJECTIVE Medical plants, as rich sources of natural antioxidants with antidiabetic effects, are used worldwide to diminish a variety of symptoms and many diseases. R. ribes L., which belongs to the family of polygonaceae, can provide symptomatic relief and assist in the prevention of the secondary complications of the diabetes. MATERIAL AND METHODS 36 female adult rats were randomly divided ...

background & aim: diabetes mellitus often has been referred to as a syndrome of disordered metabolism, usually due to a combination of hereditary and environmental causes, resulting in abnormal of high blood sugar levels (hyperglycemia). nowadays, no-drug treatments (medicinal plants) are novel therapeutic approaches in the treatment of diabetes. experimental: this study aimed at assessing ...

Since the discovery of alloxan diabetes in 1943 (l), several investigators have discussed the possibility that alloxan might be involved in some way in the pathogenesis of diabetes mellitus. Dunn et al. (1) considered this on the ground that alloxan was chemically related to uric acid. Lazarow (2) reviewed the possible relation of alloxan to diabetes and discussed the pro_ tective mechanism of ...

In the present study male albino rats weighing 200 ± 50 g were made diabetic by injection with a single ip dose of alloxan (100 mg/kg). Another group of rats was simultaneously treated with alloxan (100 mg/kg) and a single ip dose of zinc chloride (ZnCl2) (5 mg/kg). Blood and tissue samples were collected at 24, 48 and 72 hours posttreatment in both groups. Plasma insulin was significantly high...

This study investigated the behavioral and biochemical parameters of DM1 as a risk factor in an animal model of schizophrenia (SZ). All groups: 1 Control (saline+saline); 2 Alloxan (alloxan+saline); 3 Ketamine (saline+ketamine); 4 (Alloxan+Ketamine) were fasted for a period of 18h before the subsequent induction of DM via a single intraperitoneal (i.p) injection of alloxan (150mg/kg). From the ...

Ziprasidone Capsules contain a monohydrochloride, monohydrate salt of ziprasidone. Chemically, ziprasidone hydrochloride monohydrate is 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6chloro-1,3-dihydro-2H-indol-2-one, monohydrochloride, monohydrate The empirical formula is C21H21ClN4OS · HCl · H2O and its molecular weight is 467.42. Ziprasidone hydrochloride monohydrate is a white to s...

  Impaired wound healing is a well-documented complication in diabetes mellitus. With respect to the mechanism involved in impairment of wound healing in diabetic subjects and also the biological effects of fish oil and ω-3 fatty acids, in this study it was tried to examine whether fish oil-rich diet accelerates wound healing in diabetic rats or not? The adult male rats were divided into six gr...