The prognostic significance of AgNOR proteins in stage II-III rectal cancers treated with chemoradiotherapy was evaluated. Silver staining was applied to the 3μm sections of parafin blocked tissues from 30 rectal cancer patients who received 5-FU based chemoradiotherapy from May 2003 to June 2006. The microscopic displays of the cells were transferred into the computer via a video camera. AgNOR...

Preinvasive & invasive cervical lesions are a major public health concern, though it is a preventable problem to a great extent. At present few reports have been published concerning the variability of proliferative activity in cervical biopsy in women with cervical neoplastic damage. Again though the association between HPV & neoplastic cervical lesions is well known, only a few studies have b...

BACKGROUND The health risks of crack cocaine smoking on the oral mucosa has not been widely researched and documented. OBJECTIVE The purpose of this study was to analyze the proliferative activity of oral epithelial cells exposed to crack cocaine smoke using silver nucleolar organizer region (AgNOR) staining. METHODS Oral smears were collected from clinically normal-appearing buccal mucosa ...

A new staining method for dual demonstration of Estrogen receptors (ER) and argyrophilc Nucleolus-Organizer Regions (AgNORs) was developed. To rule out possible reciprocal effects, serial slides of 10 invasive ductale breast cancers were stained with either the single staining method or the simultaneous ER/AgNOR-staining method and investigated comparatively. By measuring the slides with the im...

argyrophilic staining of nucleolar organizer regions (agnor) has been considered to be useful in the diagnosis and prognostic evaluation of different cutaneous tumors. in order to evaluate the role of the agnor technique in discriminating aggressive from non-aggressive basal cell carcinoma (bcc), paraffin-embedded histologic sections from 30 cases of aggressive bcc (bcc2) and 30 cases of non-ag...

Material and Methods: The present study was conducted on 40 specimens of breast carcinoma out of which 12 cases were of Grade II and 28 cases were of Grade III. Percentage positivity and scoring of Ki-67 and mean AgNOR count was done with relation to grades. Observations: Ki-67 positivity was seen in 12 cases with the percentage positivity of 2.33±5.516 in grade II and 9.67±7.671 in grade III t...

Argyrophilic staining of nucleolar organizer regions (AgNOR) has been considered to be useful in the diagnosis and prognostic evaluation of different cutaneous tumors. In order to evaluate the role of the AgNOR technique in discriminating aggressive from non-aggressive basal cell carcinoma (BCC), paraffin-embedded histologic sections from 30 cases of aggressive BCC (BCC2) and 30 cases of n...

The objective of this study was to evaluate the cellular proliferative potential of oral lichen planus (OLP) lesions from patients without hepatitis C virus (HCV) by means of AgNOR method, as well as the cellular proliferative potential of the normal oral mucosa from patients with HCV, treated or untreated by interferon and ribavirin. A cross-sectional study was developed to investigate four gr...

The use of Toombak has been reported to play a major role in the etiology of oral cancer in Sudan. The cellular proliferative activity on the oral epithelium of 210 Toombak dippers was assessed by applying the micronuclei frequency, mean argyrophilic nucleolar organizer region (AgNOR) counts, Papanicolaou method, and 1% crystal violet stain. Participants were divided into 3 groups: 200 were app...