Gametes of the unicellular green alga Chlamydomonas reinhardtii undergo sexual adhesion via enormous chimeric Hyp-rich glycoproteins (HRGPs), the plus and minus sexual agglutinins, that are displayed on their flagellar membrane surfaces. We have previously purified the agglutinins and analyzed their structural organization using electron microscopy. We report here the cloning and sequencing of ...

It has been the uniform experience of investigators studying experimental plethora that plethora can be artificially induced by the transfusion of blood into an homologous animal. After the plethora has reached a maximum, there frequently follows an anemia, sufficiently severe in some cases to cause death. Theories have been offered to explain the mechanism of this blood destruction but the exp...

BACKGROUND AND PURPOSE Widal test is frequently applied for the detection of Salmonella agglutinins to diagnose Salmonella enterica serotype Typhi infection. There are however a number of controversies challenging the diagnostic utility of this test. This study was performed to determine the prevalence of Salmonella agglutinins in patients with other febrile illnesses and healthy blood donors. ...

Chlamydomonas flagellar sexual agglutinins are responsible for the adhesion of opposite mating-type (plus and minus) gametes during the first stages of mating. Purification and partial characterization of the plus agglutinin was previously reported (Adair, W. S., C. J. Hwang, and U. W. Goodenough, 1983, Cell, 33:183-193). Here we characterize the purified minus molecule. We show it to be a high...

1. The blood of guinea pigs convalescent from Old World and New World typhus infection develops agglutinating properties for the tunica and rat Rickettsiae of the New World diseases and for the louse Rickettsia of the Old World disease. 2. The two microorganisms are closely related, though probably not identical. 3. Human convalescents of both varieties of typhus develop agglutinins for both ty...

1. Rabbits that had received repeated intravenous injections of heat-killed indifferent streptococci with no resulting sensitization were subsequently made skin-sensitive to them by repeated intracutaneous injection of heat-killed vaccine. 2. Serum agglutinins and precipitins developed earlier in rabbits that had received repeated intravenous injections of killed streptococci and pneumococci th...