The perioperative inflammatory response is associated with outcome after complex aortic repair. Macrophage migration inhibitory factor (MIF) shows protective effects in ischemia-reperfusion (IR), but also adverse pro-inflammatory effects in acute inflammation, potentially leading to adverse outcome, which should be investigated in this trial. This prospective study enrolled 52 patients, of whom...

Background: Maternal parvovirus B19 infection can lead to serious consequences in the fetus including fetal death, non-immune hydrops fetalis and possibly long-term adverse neurodevelopmental outcome. To date, there has been no systematic review of the literature regarding long-term outcomes of these infants and children. Objective: To systematically review the literature on the long-term neuro...

Pregnant women are more susceptible to complications from respiratory disease due physiological changes in pregnancy. Coronavirus 2019 (COVID-19) like its ancestors, severe acute syndrome coronavirus (SARS-CoV) and Middle-East (MERS-CoV), may be associated with course pregnancy possible adverse outcome mother the newborn baby. Here, we present a case of pregnant lady COVID-19 oligohydraminos le...

Background We know from previous studies that increasing age, abnormal vital signs and abnormal acid-base status are strongly associated with in-hospital mortality in unselected patients admitted acutely to hospital. A model including this information will make us able to explore associations and predict the risk for future patients. Our aim was to describe a Bayesian model for prediction of ad...

Over the last decade there has been growing interest in “bedside” protein and cellular markers of inflammation and adverse outcome after acute myocardial infarction (AMI) (1–16). In this issue of the Journal, Maekawa et al. (17) address the prognostic significance of peripheral monocytosis found at two to three days after reperfused AMI as a cellular marker for clinical outcome and its possible...

INTRODUCTION AND OBJECTIVES Few data are available on the outcome of patients admitted to hospital with suspected acute coronary syndrome who have no high-risk factors and who undergo exercise testing before discharge. Our objectives were to investigate outcomes in this group of patients and to determine whether clinical history-taking or exercise testing can help to predict outcome. PATIENTS...