OBJECTIVE To evaluate the existence of an association between cervicovaginal infections and precancerous lesions of the uterine cervix, through determination of prevalent cervicovaginal micro-organisms, alone and in association with human papillomavirus (HPV), in patients with abnormal and normal vaginal cytology. PATIENTS AND METHODS Patients with abnormal vaginal cytology were divided into ...

BACKGROUND Cervical cancer can be prevented by early detection and treatment for precancerous lesions. Since 1995, there has been a national cervical cancer screening program in Norway, where women aged 25-69 years are recommended to take Pap smears every three years. There are 17 cytology laboratories covering a population of 5 million people. The detection rate of cervical abnormalities varie...

Human papillomavirus (HPV) testing is used in primary cervical screening, as an adjunct to cervical cytology for the management of low grade abnormal cytology, and in a test of cure. PapilloCheck (Greiner Bio-One) is a PCR-based DNA microarray system that can individually identify 24 HPV types, including the 13 high-risk (HR) types identified by Hybrid Capture 2 (HC2). Here, we compare PapilloC...

OBJECTIVE Evaluating the opportunity and access to diagnosis and treatment for females having had an abnormal Pap smear (high-grade epithelial lesion and cervical cancer) in Colombia from June 2005 to June 2006. MATERIALS AND METHODS This was a retrospective appraisal using a semi-closed survey of females having had an abnormal Pap smear with high squamous intraepithelial lesions or cervical ...

OBJECTIVE To determine the frequency of different outcomes in women participating in cervical screening. DESIGN Analysis of screening records from 348 419 women, and modelling of cases of cervical cancer and deaths with and without screening. SETTING Cervical screening programme in Bristol. RESULTS For every 10 000 women screened from 1976 to 1996, 1564 had abnormal cytology, 818 were inv...

The objective of this study was to determine the prevalence of significant lesions defined as high grade squamous intraepithelial lesions (HSIL), adenocarcinoma in situ (AIS) and invasive carcinoma in women who had HPV-positive and cytology negative co-testing screening results. This retrospective study was conducted in Chiang Mai University Hospital between May, 2013 and August, 2014. Hybrid c...

Over the past 50 years, the incidence and mortality of cervical cancer has decreased by 75 percent in developed countries because of the availability of screening program for cervical precancer and human papilloma virus (HPV) vaccination. In developing countries, however, cervical cancer remains the second most common type of cancer and cause of cancer death in women. This is most likely due to...

background and objective: the aim of this study was to compare the screening performance of a new modified liquid-based cytology method (liquiprep™) with conventional pap smear (cp) in a low risk population, using colposcopy followed by histology as “gold standard”. patients and methods:  this cross-sectional study was performed on random referred specimens to a general gynecological clinic in ...

OBJECTIVES The aim of this study was to evaluate the diagnostic accuracy of sensitivity and specificity of cervical lesions by the low-cost, portable Gynocular colposcope and a stationary colposcope, in women referred for colposcopy with abnormal cervical cytology. METHODS A randomized cross-over clinical trial for evaluating the diagnostic accuracy in detecting cervical lesions by the Gynocu...

INTRODUCTION We evaluated colposcopy in the routine diagnostic workup of women with abnormal cervical cytology, as well as the diagnostic value of endocervical curettage material and biopsies taken from colposcopy-positive and colposcopy-negative quadrants of the cervix. MATERIAL AND METHODS This cross-sectional study included 297 nonpregnant women with abnormal cervical cytology and no prior...