The retina has a high rate of oxygen consumption, and the retinal vessels are knoion to constrict with increased arterial oxygen tension and dilate ivhen arterial oxygen falls. In 10 subjects, measurement of retinal venous oxygen saturation by a photographic technique has shown an increase from 55 ± 8 per cent saturation breathing air to 82 ± 9 per cent breathing 100 per cent Os. This increase ...

PURPOSE To study the feasibility of performing retinal endovascular surgery with a microfabricated needle-based cannulation system at the level of the retinal microvasculature. METHODS A total of 40 retinal vein vessels, and 40 porcine eyes were used, and the eyecups were prepared under an operating microscope. Twenty retinal veins each were pierced with a microfabricated needle having an out...

Breakdown in the blood-retinal barrier occurs in retinal neovascularization in a number of diseases. To study the anatomic basis of this breakdown, we examined retinal neovascularization induced by injection of 250,000 homologous fibroblasts into the vitreous cavity of pigmented rabbits. Neovascularization is evident by electron microscopy in this model 3 days after fibroblast injection. Fluore...

The aim of the study was to investigate the correlation between the levels of C-reactive protein (CRP) and chitinase 3-like protein 1 (YKL-40) in blood samples with morpohometric parameters of retinal blood vessels in patients with diabetic retinopathy. Blood laboratory examination of 90 patients included the measurement of glycemia, HbA1C, total cholesterol, LDL-C, HDL-C, triglycerides and CRP...

BACKGROUND Segmental glomerulosclerosis without significant mesangial or endocapillary proliferation is rarely seen in IgA nephropathy (IgAN), which simulates idiopathic focal segmental glomerulosclerosis (FSGS). We recently recognized aberrant blood vessels running through the adhesion sites of sclerosed tufts and Bowman's capsule in IgAN cases with mild glomerular histologic change. METHODS...

The segmentation of retinal blood vessels in the retina is a critical step in diagnosis of diabetic retinopathy. In this paper, we present a new method for automatically segmenting blood vessels in retinal images. Five basic algorithms for segmenting retinal blood vessels, based on different image processing techniques, are described and their strengths and weaknesses are compared. A hybrid alg...

In this paper, a system for automated analysis of retinal images is proposed. This system segments blood vessels in retinal images and recognizes the main features of the fundus on digital color images. The recognized features were defined as blood vessels, optic disc, and fovea. An algorithm called 2D matched filters response has been proposed for the detection of blood vessels. Also, automati...