The androgen receptor (AR) encoding gene can undergo mutations during the development and treatment of prostate cancer. Even in hormone-independent stages, mutations in the receptor paradoxically seem to result in an increased AR function. Two such point mutations have been described in the part of the AR involved in DNA binding and nuclear translocation, namely the hinge region. Despite a decr...

BACKGROUND Natalizumab has shown its efficacy in reducing multiple sclerosis (MS) relapses and progression of disability; however, it has been associated with an increased risk of developing progressive multifocal leukoencephalopathy (PML). The differential expression of microRNA (miRNA), the small non-coding RNAs that regulate gene expression, in natalizumab-treated patients has been reported ...

Introduction: Personality characteristics are believed to predict post-transplant adherence and outcome. However, data concerning the prevalence and type of personality disorders (PDs) among transplant populations are sparse. Objectives: To evaluate the prevalence and types of PDs among patients waiting for liver or kidney transplants, to compare the results obtained between the two groups and ...

The active region, AR0554, was observed with NIS/CDS on board SoHO to examine the extent and range of oscillations from a range of features. Among all the NIS spectral lines analysed, significant oscillations were found in Si xii 520 Å, Mg x 625 Å, O v 629 Å, and He i 522 Å. The periods of the strongest oscillations in these lines were ≈ 10–20 min. After the dominant 10–20 min oscillations were...

Taking into account the shortcomings of information exchange system through ARINC 629 bus, which is widely used in new digital avionics systems (delay exchange, program errors, sensitivity to external influences, etc.), fiber-optic proposed article reduces weight aircraft aviation systems, it allows solving many problems such as software delays and maintenance problems. This has a much higher t...

Die akademische Selbstwirksamkeit ist einer der wichtigsten Faktoren, die Leistung von Studierenden in ihren Lernprozessen beeinflussen. Ziel dieser Studie es, an Fakultäten, Hochschulen und Berufsfachhochschulen durch einen Vergleich nach Geschlecht, Klasse Leistungsmerkmalen zu untersuchen. wurde 629 Universitäten Necmettin Erbakan Kırklareli durchgeführt. Zur Erhebung Forschungsdaten eine Sk...