نتایج جستجو برای: 549 cell line

تعداد نتایج: 1970969  

Journal: :international journal of preventive medicine 0
shabnam nadjafi soltan-ahmad ebrahimi nahid rahbar-roshandel

background: oligodendrocytes, the myelinating glial cells of central nervous system, are highly vulnerable to ischemic‑induced excitotoxic insult, a phenomenon in which calcium overload triggers cell death. berberine is an alkaloid extracted from medicinal herbs as coptidis rhizoma with several pharmacological effects like inhibition of neuronal apoptosis in cerebral ischemia. methods: we exami...

Journal: :research in pharmaceutical sciences 0
somayeh atari-hajipirloo 1department of biochemistry , student research committee,urmia university of medical sciences, urmia, i.r. iran. saba nikanfar 2department of biochemistry, urmia university of medical sciences, urmia, i.r. iran. amir heydari 3department of pharmacology, cellular and molecular research center, urmia university of medical sciences, urmia, i.r. iran. fatemeh kheradmand 4department of clinicalbiochemistry, cellular and molecular and solid tumor research center, urmia university of medical sciences, urmia, i.r. iran.

mono-targeting by imatinib as a main antitumor agent does not always accomplish complete cancer suppression. 2,5-dimethyl-celecoxib (dmc) is a close structural analog of the selective cyclooxygenase-2 (cox-2) inhibitor, celecoxib, that lacks cox-2 inhibitory function. in this study, we aimed to show the apoptotic effects of imatinib in combination with dmc in human ht-29 colorectal cancer (crc)...

Journal: :iranian journal of radiation research 0
s.m.j. mortazavi department of medical physics and medical engineering , school of medicine, shiraz university of medical sciences, shiraz, iran n. erfani shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz, iran h. mozdarani department of medical genetics, faculty of medical sciences, tarbiat modares university, tehran, iran r. azmoonfar radiology department, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran n. shokrpour school of paramedical sciences, shiraz university of medical sciences, shiraz, iran

background: radiation-induced bystander effect is a response which results in damage in non-irradiated cells in response to signals from the irradiated cells. the aim of the present study was to investigate microwave-induced bystander effect from a gsm mobile phone simulator on induction of apoptosis in jurkat cell line. materials and methods: jurkat cells were divided into three groups of non-...

Journal: :basic and clinical neuroscience 0
sareh kazmi laya kafami ahmad ebrahimi behnam jameie mohammad taghi joghataiee

introduction: oxidative stress and neuroinflammation are involved in neurodegeneration procedure in parkinson’s disease. recently, neuroprotective potential of boswellia resin has been demonstrated. therefore, this study examined whether administration of boswellia resin would attenuate mpp+- induced neuronal death in sk-n-sh- cell line, a human dopaminergic neurons- in vitro. methods: boswelli...

Journal: :Applied Nanoscience 2021

The synthesis and biomedical applications of nano/micromotors have attracted great attention. In this work, preparation characterization catalytic gold/poly(3,4-ethylenedioxythiophene)/platinum (Au/PEDOT/Pt) micromotors were reported to present their contribution for cancer biomarker miRNA-21 detection. Potential use these motors possible treatment was also illustrated after biocompability had ...

2017
Wen-dong Wang Yan Liu Yuan Su Xian-zhi Xiong Dan Shang Juan-juan Xu Hong-ju Liu

BACKGROUND The main aim of this study was to demonstrate the antitumor potential of cucurbitacin A on A-549 NSCLC (non-small cell lung cancer cells). The effects of Cucurbitacin A on apoptotic induction, cell physic, cell cycle failure and m-TOR/PI3K/Akt signalling pathway were also investigated in the present study. MATERIALS AND METHODS MTT assay and clonogenic assay were carried out to stu...

2013

The bovine adenosine triphosphate-binding cassette transporter G2 (ABCG2/breast cancer resistance protein) polymorphism Tyr581Ser (Y581S) has recently been shown to increase in vitro transepithelial transport of antibiotics. Since this transporter has been extensively related to the active secretion of drugs into milk, the potential in vivo effect of this polymorphism on secretion of xenobiotic...

2013

The bovine adenosine triphosphate-binding cassette transporter G2 (ABCG2/breast cancer resistance protein) polymorphism Tyr581Ser (Y581S) has recently been shown to increase in vitro transepithelial transport of antibiotics. Since this transporter has been extensively related to the active secretion of drugs into milk, the potential in vivo effect of this polymorphism on secretion of xenobiotic...

2013
Cristina Delgado-Andrade Irene Roncero-Ramos José Carballo José Ángel Rufián-Henares Isabel Seiquer Pilar Navarro

Our aim was to investigate the effects of Maillard reaction products (MRPs) from bread crust (BC) on bone composition and its mechanical properties, determining whether any such effects are related to the molecular weight of different MRPs. For 88 days after weaning rats were fed a control diet or diets containing BC, or its soluble low molecular weight (LMW), soluble high molecular weight (HMW...

2013
A. OTERO

The bovine adenosine triphosphate-binding cassette transporter G2 (ABCG2/breast cancer resistance protein) polymorphism Tyr581Ser (Y581S) has recently been shown to increase in vitro transepithelial transport of antibiotics. Since this transporter has been extensively related to the active secretion of drugs into milk, the potential in vivo effect of this polymorphism on secretion of xenobiotic...

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