The green fluorescent protein (GFP) is a widely used reporter in gene expression and protein localization studies. GFP is a stable protein; this property allows its accumulation and easy detection in cells. However, this stability also limits its application in studies that require rapid reporter turnover. We created a destabilized GFP for use in such studies by fusing amino acids 422-461 of th...

Bu çalışmanın amacı rekreasyon liderlik davranışlarını belirlemeye yönelik ölçüm aracı geliştirmektir. Hazırlanan denemelik nihai form ilk aşamada 422 öğrenci ile test edilmiş, çalışma grubu büyüklüğünün yeterliliği analiz edilmiştir (.85; 1766. 834, p

OBJECTIVE To retrospectively analyze and compare the ultrasonographic characteristics and BI-RADS-US classification between patients with BRCA1 mutation-associated breast cancer and those without BRCA1 gene mutation in Guangxi, China. METHODS The study was performed in 36 lesions from 34 BRCA1 mutation-associated breast cancer patients. A total of 422 lesions from 422 breast cancer patients w...

We introduce a small cost of leading (small gain from waiting) in the two-player action commitment game formulated by Hamilton and Slutsky (1990). We investigate a quantity competition model with linear demand and constant marginal costs. We find that there exists a unique randomized strategy equilibrium as long as the leading cost is positive and not too large. The randomized strategy equilibr...

The activation of the AGC (protein kinase A/protein kinase G/protein kinase C)-family kinase SGK1 (serum- and glucocorticoid-induced kinase 1) by insulin via PI3K (phosphoinositide 3-kinase) signalling has been appreciated for almost 10 years. PDK1 (phosphoinositide-dependent protein kinase 1), a kinase that phosphorylates the SGK1 catalytic domain at Thr(256), is known to play a critical role ...

*Correspondence: Baskiran Adil, Elazig Road, 15th km, Inonu University School of Medicine, Department of Surgery, Malatya, Turkey 44280 Tel: +90-422-341-06 60-6416 Fax: +90-422-341-0660 E-mail: [email protected] The intra-operative death of a liver transplant recipient is a devastating complication that occurs very infrequently. If the liver graft is exactly procured from the living do...

Hans Schneider (Hg.), Das Augustinerkloster Alsfeld. Beiträge zu seiner Geschichte (Veröffentlichungen der Historischen Kommission für Hessen, Bd. 89). Marburg 2019. X, 422 S., 102 Abb. ISBN 978-3-942225-47-2. Geb. € 28,–