ABSTRACT. Among oxygen-containing heterocyclic compounds such as coumarin and azacoumarin derivatives, the scaffold has become an important construction motif for developing new drugs. Coumarin its derivatives possess many types of biological activities have been reported to show significant cytotoxic activity. N-(6,8-disubstituted coumarin-3-yl)benzamides (8a-c) namely (3-N-(benzoyl) aminocoum...

In the mol-ecule of the title compound, C(17)H(10)BrNO(5), the indoline system and the attached coumarin ring are each essentially planar with maximum deviations of 0.074 (2) and 0.062 (2) Å, respectively. The dihedral angle between them is 85.09 (3)°. In the crystal, all heteroatoms (except for the coumarin oxo O atoms) are involved in intra- and inter-molecular hydrogen bonds. An intra-molecu...

The crystal structure of ( R , )-4-bromo-2-{4-[4-bromo-1-(4-toluenesulfonyl)-1 H -pyrrol-2-yl]-1,3-dinitrobutan-2-yl}-1-(4-toluenesulfonyl)-1 -pyrrole 1 C 26 24 Br 2 N 4 O 8 S ) is presented. title compound was isolated in suitable yield as a by-product our synthesis geminal -dimethyl hydrodipyrrins. We observe an unforeseen enantiomeric resolution both the bulk sample and with distinct C—H...O...