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1. Macdougall IC. Once-weekly erythropoietic therapy: is there difference between the available preparations? Nephrol Dial Transplant 2002; 17: 2047–2051 2. Locatelli F, Olivares J, Walker R et al. on behalf of the European/Australian NESP 980202 Study Group. Novel erythropoiesis stimulating protein for treatment of anemia in chronic renal insufficiency. Kidney Int 2001; 60: 741–747 3. Nissenso...
We report a case of skin rashes that occurred in a 20-year-old South Indian female of Pittakaphala prakruthi (constitution) after beginning therapy with Aragwadadi kashaya (poly-herbal formulation) and syp talekt (poly-herbal patent formulation) for the treatment of reccurent incidence of abscess. Rash disappeared after stopping the suspected drug and treatment with Vibhitaki kashaya (decoction...
The purpose of this study was to determine the effect of self-stimulation of the parasympathetic nervous system on immune function and DNA repair function in family caregivers. Seven female family caregivers engaged in individually tailored stimulation of the parasympathetic nervous system in everyday life for 2 weeks. Although we observed effects on lymphocyte function and secretory immunoglob...
Alopecia areata (AA) is a common and distressing condition in populations worldwide. The course of this condition is unpredictable and remains elusive. Patients with AA have a negative appraisal of their self-image, resulting in a demand for any effective treatment options. Hair transplantation might be considered for those patients who have exhausted standard clinical therapies for a period of...
Epidermal growth factor receptor (EGFR) and its ligands amphiregulin (AREG) and epiregulin (EREG) play a central role in the development of colorectal cancer, but the prognostic values of AREG and EREG are controversial. We conducted a meta-analysis of studies that investigated AREG and/or EREG mRNA levels in primary tumors to determine their prognostic value in metastatic colorectal cancer (mC...
The pathogenic fungus Candida albicans causes disseminated candidiasis with a poor prognosis in immunocompromised hosts. Secreted aspartyl protease (Sap) from the microorganism acts as a hydrolase to facilitate invasion into host tissues. Inhibition of Candida Sap activity could be a new treatment strategy for candidiasis. In the present study, we screened compounds from an FDA-approved drug li...
Cytosolic ferritin sequesters and stores iron and, consequently, protects cells against iron-mediated free radical damage. However, the function of the newly discovered mitochondrial ferritin (MtFt) is unknown. To examine the role of MtFt in cellular iron metabolism, we established a cell line that stably overexpresses mouse MtFt under the control of a tetracycline-responsive promoter. The over...
120 residents with dementia in long term care facilities were recruited for the study. Pittsburg Agitation Scale was used to screen for the presence of BPSD. 60 patients were in the control group and 60 patients in the study group. Construct and criteria validity was established by comparing LuBAIR to BEHAVE-AD and Cohen-Mansfield Agitation Inventory. Intraand inter-rater reliability of LuBAIR ...
Centromeres of higher eukaryotes are epigenetically defined by the centromere specific histone H3 variant CENP-A(CID). CENP-A(CID) builds the foundation for the assembly of a large network of proteins. In contrast to mammalian systems, the protein composition of Drosophila centromeres has not been comprehensively investigated. Here we describe the proteome of Drosophila melanogaster centromeres...
BACKGROUND AND PURPOSE Despite moderate heritability, the phenotypic heterogeneity of ischemic stroke has hampered gene discovery, motivating analyses of diagnostic subtypes with reduced sample sizes. We assessed evidence for a shared genetic basis among the 3 major subtypes: large artery atherosclerosis (LAA), cardioembolism, and small vessel disease (SVD), to inform potential cross-subtype an...
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