Mice expressing the immunoglobulin (Ig) heavy (H) chain variable (V) region from a rearranged V(H)12 gene inserted into the IgH locus generate predominantly B-1 cells, whereas expression of two other V(H) region transgenes (V(H)B1-8 and V(H)glD42) leads to the almost exclusive generation of conventional, or B-2, cells. To determine the developmental potential of B cells bearing two distinct B c...

The mAb B1 (mouse IgG1 kappa) recognizes a carbohydrate epitope on human carcinoma cells (I. Pastan et al., Cancer Res., 51: 3781-3787, 1991). We have generated plasmids encoding immunotoxins in which the Fv domain of B1, either as a single-chain Fv or as a disulfide-stabilized Fv (dsFv), was fused to PE38, a truncated form of Pseudomonas exotoxin A. To compare the activities of the two types o...

We investigate the relations between the cut number, c(M), and the first Betti number, b1(M), of 3-manifolds M. We prove that the cut number of a “generic” 3-manifold M is at most 2. This is a rather unexpected result since specific examples of 3-manifolds with large b1(M) and c(M) ≤ 2 are hard to construct. We also prove that for any complex semisimple Lie algebra g there exists a 3-manifold M...

In this paper the intersection problem for a pair of kite-GDDs type 4u is investigated. The determination all pairs (T, s) such that there exists (X,H,B1) and (X,H,B2) same T |B1?B2| = s. Let J(u) {s : ? intersecting in s blocks}; I(u) {0, 1,..., bu 2, bu}, where 2u(u 1) number blocks kite-GDD 4u. We show any positive integer u 3, I(u).

Protein content is one of the main factors determining end-use quality wheat. NO APICAL MERISTEM-B1 (NAM-B1) a major gene regulating wheat grain protein content. The present study aimed to identify new genetic resources using wild-type NAM-B1 allele breed high-protein-content cultivars. We genotyped HIGH GRAIN PROTEIN CONTENT-B1 (GPC-B1) locus and in 165 A kompetitive allele-specific polymerase...

The B1 SOX transcription factors SOX1/2/3/19 have been implicated in various processes of early embryogenesis. However, their regulatory functions in stages from the blastula to early neurula remain largely unknown, primarily because loss-of-function studies have not been informative to date. In our present study, we systematically knocked down the B1 sox genes in zebrafish. Only the quadruple ...

Our main task of this lecture is to show a polynomial time algorithm which approximately solves the Shortest Vector Problem (SVP) within a factor of 2 for lattices of dimension n. It may seem that such an algorithm with exponential error bound is either obvious or useless. However, the algorithm of Lenstra, Lenstra and Lovász (LLL) is widely regarded as one of the most beautiful algorithms and ...

DtmING A STUDY concerning the role of vitamin B1, in diabetes (1), it was noted that a number of cases in this study failed to excrete more than 10 gig. of a 50Lg. intramuscular load dose of the vitamin. All of these patients had a history of liver disease or some form of hepatic insufficiency. The storage of vitamin B1, by the liver has been studied extensively by Meyer et at. (2) and by Glass...

The aim of this paper is to present an answer to Problem 1 of [M1], [M2]. We do this by proving in particular that if μ is a strong limit singular cardinal, θ = (2), 2 = μ then there are Boolean algebras B1,B2 such that c(B1) = μ, c(B2) < θ but c(B1 ∗ B2) = μ. Further we improve this result, deal with the method and the neccessity of the assumptions. The research partially supported by “The Isr...

Let G be a graph, u be a vertex of G, and B(u)(or BG(u)) be the set of u with all its neighbors in G. A sequence (B1, B2, ..., Bn) of subsets of an n-set S is a neighborhood sequence if there exists a graph G with a vertex set S and a permutation (v1, v2, ..., vn) of S such that B(vi) = Bi for i = 1, 2, ..., n. Define Aut(B1, B2, ..., Bn) as the set {f : f is a permutation of V (G) and (f(B1), ...