The products of infection with Vibrio comma (Vibrio cholerae), which are responsible for the severe purging diarrhea characteristic of the disease, have not yet been clearly demonstrated. To provide a rational basis for development of more efficient immunization practices, such information on the relation of vibrio products to specific pathology is required. Various kinds of toxic materials fro...

An antimicrobial validatory screening of short nosed tripod fish Triacanthus biaculeatus (Bloch, 1786) collected from the Visakhapatnam coastal waters, India is done in such a way T. biaculeatus muscle extracts were subjected for antimicrobial assay. Antimicrobial screening assay was done in five bacterial pathogens viz., Escherichia coli (MTCC-443), Salmonella typhi (MTCC-421), Pseudomonas aer...

BACKGROUND Cholera, an ancient scourge, continues to inflict high rates of mortality today. The rising incidence of epidemics in areas of poor sanitation and crowding highlight the need for better epidemic prevention and early response. Such interventions require the availability of rapid and accurate diagnostic techniques to trigger timely response and mitigate the scale of the outbreak. The c...

Both specific polyclonal antiserum and monoclonal antibodies against mannose-binding hemagglutinin fimbriae of Vibrio cholerae (mannose-sensitive hemagglutinin [MSHA]) were shown to protect against experimental cholera caused by vibrios of the El Tor biotype in the infant mouse and in the rabbit intestinal loop models. MSHA-specific Fab immunoglobulin fragments were also protective. No protecti...

Antiserum to the capsular polysaccharide of an opaque variant of Vibrio cholerae O139 strain MDO-12 recognizes capsular antigen in three different colonial variants of the strain, although the amount of recognition varies with the extent of opacity. The anti-capsular-polysaccharide serum, at subagglutinating doses, protected suckling mice against challenge with both the most opaque variant and ...

We present the draft genome sequence of Vibrio cholerae InDRE 3140 recovered in 2013 during a cholera outbreak in Mexico. The genome showed the Vibrio 7th pandemic islands VSP1 and VSP2, the pathogenic islands VPI-1 and VPI-2, the integrative and conjugative element SXT/R391 (ICE-SXT), and both prophages CTXφ and RS1φ.

BACKGROUND & OBJECTIVES Factor causing the elimination of the classical biotype of Vibrio cholerae O1, and its replacement by the El Tor biotype causing the 7 th cholera pandemic are unclear. Possible ability of the El Tor strains to adapt better than the classical strains to undefined environmental forces have been largely implicated for the change. Here we describe an environmental bacterioph...

The bacterium Vibrio cholerae is the cause of cholera. Cholera spread through feces an infected individual in a population. From mathematical point view, this problem can be brought into model form Susceptible-Infected-Recovered (SIR), which considers birth rate. Because outbreaks that occur easily if not treated immediately, it necessary to control susceptible population by vaccination. vaccin...

Cholera in the nineteenth century has proved an enduring topic for historians. In 1961 Asa Briggs called for analysis of cholera as an under-utilized yet potentially powerful tool for the emerging discipline of social history.2 Researchers in the field responded with a plethora of works on this most brutal of epidemic diseases. Despite methodological and interpretative differences, the literatu...