نتایج جستجو برای: urinary citrate
تعداد نتایج: 122279 فیلتر نتایج به سال:
In a colony of germfree rats 50 per cent of the males had urinary calculi composed of calcium citrate and calcium oxalate. Genetically closely related conventional animals on the same sterilized diet did not present a single case of stone formation. The tendency to calculus formation disappeared when germfree animals were contaminated with the intestinal flora from conventional rats. The calcul...
BACKGROUND Kidney stones affect people worldwide and have a high rate of recurrence even with treatment. Recurrences are particularly prevalent in people with low urinary citrate levels. These people have a higher incidence of calcium phosphate and calcium oxalate stones. Oral citrate therapy increases the urinary citrate levels, which in turn binds with calcium and inhibits the crystallisation...
Purpose. To use in vitro and in vivo models to evaluate Glechoma longituba extract to provide scientific evidence for this extract's antiurolithic activity. Materials and Methods. Potassium citrate was used as a positive control group. Oxidative stress (OS) markers and the expression of osteopontin (OPN) and kidney injury molecule-1 (KIM-1) were measured to assess the protective effects of Glec...
OBJECTIVE To evaluate the prevalence of metabolic disorders associated with nephrolithiasis in a female population. METHODS A retrospective study on 1,737 patients with evidence of recent formation of renal stones, being 54% females. The laboratory investigation consisted of at least two samples of blood and 24-hour urine to assess calcium, uric acid, citrate and creatinine levels, qualitativ...
Background: We sought to assess the strength of the evidence for long-term lemonade therapy on urinary citrate excretion and stone formation in patients with hypocitraturic nephrolithiasis. Context of the study: A literature search was conducted via PubMed (1970–June 2015) using the key terms “lemonade” and “hypocitraturic nephrolithiasis,” as well as the Medical Subject Headings “medical thera...
Objective The objective of this study was to evaluate the role of oxidative stress in an experimental model of streptozotocin-induced diabetic nephropathy in rats. Materials and methods Wistar, adult, male rats were used in the study. Animals were divided in the following groups: Citrate (control, citrate buffer 0.01M, pH 4.2 was administrated intravenously - i.v - in the caudal vein), Uninep...
OBJECTIVE To analyze the clinical evidence on the efficacy of phytotherapy in the treatment of calculi in the urinary tract. METHODS To be eligible, full-length articles should include the results of randomized controlled trials enrolling patients affected by urolithiasis, reporting any comparison between an experimental herbal agent versus placebo or any active comparator, aimed at preventin...
OBJECTIVE Diet interventions may reduce the risk of urinary stone formation and its recurrence, but there is no conclusive consensus in the literature regarding the effectiveness of dietary interventions and recommendations about specific diets for patients with urinary calculi. The aim of this study was to review the studies reporting the effects of different dietary interventions for the modi...
Urinary stone disease is global problem and is due to alteration in the normal crystallization environment of urine in the urinary tract systems. Major factors responsible for crystal formation are super-saturation of Ca salts and level of crystallization inhibitors (Citrate & Phytate). Excessive citrate intake makes the urine more alkaline (pH between 6 and 7). This can be achieved by oral adm...
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