Fusarium verticillioides is the most common fungal pathogen of maize in Ethiopia. Many strains this produce fumonisin myotoxins that are harmful to human and animal health. This study was conducted determine fumonisin-producing ability isolates F. isolated from kernels collected different maize- growing areas country. Eighty were grown on autoclaved cultures for one month, content quantified us...

Fusarium proliferatum is a major cause of maize ear rot and fumonisin contamination and also can cause wheat kernel black point disease. The primary objective of this study was to determine whether nine F. proliferatum strains from wheat from Nepal can cause black point and fumonisin contamination in wheat kernels. For comparison, the study included three Fusarium strains from US maize. In test...

Fumonisins are mycotoxins produced by Fusarium moniliforme, a common fungal contaminant of corn worldwide, 10 and F. proliferatum, a closely related species.l.Io.'9 The true incidence of F. moniliforme is difficult to determine because F. proliferatum has often been misidentified as F. moniliforme. lO,'3 Certain strains of F. proliferatum also produce moniliformin, but isolates of F. moniliform...

14C-Fumonisin B(1) (FB(1)) was produced by Fusarium proliferatum M-5991 in modified Myro liquid medium and purified to >95% purity with a specific activity of 1.7 mCi/mmol. Nine male and nine female F344/N rats were each dosed by gavage with 0.69 micromol of (14)C-FB(1), (14)C-hydrolyzed FB(1), or (14)C-FB(1)-fructose/kg body weight. Urinary excretion of (14)C-FB(1) and (14)C-FB(1)-fructose was...

Sphingolipids are abundant constituents of neuronal membranes and have been implicated in intracellular signaling. We show that two analogs of glycosphingolipid biosynthetic intermediates, fumonisin B1 (which inhibits dihydroceramide synthesis) and DL-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (PPMP) (which inhibits glucosylceramide synthesis) decrease glycosphingolipid synthesis in rat ...

fumonisin b1 (fb1) is the most abundant of the fumonisin mycotoxins, mainly produced in corn by fungi of the genus fusarium. fb1 has been shown to be hepatocarcinogenic and nephrocarcinogenic in animals. contamination of corn with fb1 was assayed in samples collected from mazandaran province, situated on the caspian littoral of iran, in september 2000. in this survey, 38 corn samples were analy...

The effects of cotton-corn rotation and glyphosate use on levels of soil-borne Aspergillus flavus, aflatoxin and fumonisin contamination in corn and cotton seed were determined during 2002-2005 in Stoneville, Mississippi (USA). There were four rotation systems (continuous cotton, continuous corn, cotton-corn and corn-cotton) for both glyphosate-resistant (GR) and non-GR cultivars-herbicide syst...

Fusarium verticillioides is one of the most important fungal pathogens to cause destructive diseases of maize worldwide. Fumonisins produced by the fungus are harmful to human and animal health. To date, our understanding of the molecular mechanisms associated with pathogenicity and fumonisin biosynthesis in F. verticillioides is limited. Because MAP kinase pathways have been implicated in regu...

The sphingolipid signaling pathway appears to play an important role in regulating vascular tone. We examined the effect of fumonisin B(1), a fungal toxin in corn that blocks ceramide synthase in the sphingolipid signaling pathway, on the ascending aortic impedance spectrum of pigs. Sixteen pigs were fed culture material containing fumonisin B(1) (20 mg/kg body wt) (n = 7) or a control diet (n ...