One titrimetric and two indirect spectrophotometric methods are described for the determination of doxycycline hyclate (DCH) in bulk drug and in its formulations. The methods use bromate-bromide, methyl orange and indigo carmine as reagents. In titrimetry (method A), DCH is treated with a known excess of bromate-bromide mixture in acid medium and the residual bromine is back titrated iodometric...

A method for the rapid determination of double-layer capacitancepotential curves of electrodes is described. An on-line computer is used to apply Kalousek-type waveforms to the electrochemical cell and to measure the accompanying current response. The capacitances am determined from the slope of the plots of log current against timeFor 0.1 M KCI, the computerized method agrees weli with the bri...

Hydrogen peroxide (H2O2) plays a pivotal role in various industrial applications [1]. It is an essential mediator in pharmaceutical, clinical, and environmental research. In addition, it is a byproduct of highly selective oxidases and an important contaminant in several industrial products and wastes [2]. Therefore, a reliable and economical method for the determination of H2O2 is of great sign...

This paper describes the development and evaluation of a HPLC and UV spectrophotometric methods to quantify Cefaclor Monohydrate in Oral suspensions and Capsules. HPLC analysis were carried out using a C18 Knauer column and a mobile phase composed of Triethylamine: methanol: Acetonitrile: water (2: 10: 20: 68)v\v%, with a flow rate of 1.0 mL/min and UV detection at 265 nm. For the spectrophotom...

Although the roster of coulometric titrations no\\' includes many reactions of classical titrimetry'. the lIse of cl,ectrogeneratecl +2 tin as a coulometric titrant has not previously been reported. We have found that in an acidic bromide medium +4 tin (probably SrlBr6-2) is reduced to the' +2 state (probably SnBr4-2) with 100% current efficiency' at a gold cathode. The formal potential of the ...

Abstract The quality of groundwater samples around Igando area, Lagos State, Nigeria was investigated with the aim detecting possible influence dumpsites on nearby aquifers. Thirty-seven (37) were evaluated for their suitability in drinking and agricultural purposes. Physical parameters determined situ using portable multi-meter. Flame absorption used to determine concentrations major cations w...