Accurate prediction of thrombosis in essential thrombocythemia (ET) provides the platform for prospective studies exploring preventive measures. Current risk stratification for thrombosis in ET is 2-tiered and considers low- and high-risk categories based on the respective absence or presence of either age > 60 years or history of thrombosis. In an international study of 891 patients with World...

BACKGROUND AND OBJECTIVE Health plans are increasingly using more open drug formularies that offer differential prescription copayments as an incentive to enrollees to use brands that plans prefer. How much this financial incentive affects use of preferred brands has not been widely reported. The aim of this study was to estimate the effect of tiered copayments on the choice between preferred a...

Cloud storage systems typically use three-way random replication to guard against data loss within the cluster, and utilize cluster geo-replication to protect against correlated failures. This paper presents a much lower cost alternative to full cluster geo-replication. We demonstrate that in practical settings, using two replicas is sufficient for protecting against independent node failures, ...

Multi-tiered storage systems using tiers of SSD and traditional hard disk is one of the fastest growing trends in the storage industry. Although using multiple tiers provides a flexible trade-off in terms of IOPS performance and storage capacity, we believe that providing performance isolation and QoS guarantees among various clients, gets significantly more challenging in such environments. Ex...