The 2003 version of Principles and Guidelines for Social Impact Assessment (SIA) in the USA provides guidance for the conduct of SIA within the context of the US National Environmental Policy Act of 1970. Guidelines are integrated within six principles focusing on: understanding of local and regional settings; dealing with the key elements of the human environment; using appropriate methods and...

Malay proverbs which are sourced from chicken, 90 in total. Various references of chicken have been created by the Malays to mirror behaviours and actions human beings implicitly. Each can provide lessons, advices reprimands a gentle manner still be used up today. The attributes “careful”, “useless” “betrayal” among these references. In order analyse data proverbs, research will use Inquisitive...

SOMMARIO È possibile individuare strumenti e strategie per condividere buone pratiche fra colleghi, comunicare e sfruttare efficacemente le capacità di apprendimento degli studenti, i l tutto a costi molto contenuti? E come? Con un semplice laptop, i tools cooperativi del Web 2.0 e il software Open Source. L’e-learning, sia nei suoi risvolti formali (le cosiddette “piattaforme”) che informali (...

Recent studies have shown multiple differences between humans and apes in sialic acid (Sia) biology, including Siglecs (Sia-recognizing-Ig-superfamily lectins). Comparisons with the chimpanzee genome indicate that human SIGLEC11 emerged through human-specific gene conversion by an adjacent pseudogene. Conversion involved 5 cent untranslated sequences and the Sia-recognition domain. This human p...

Abstract The sulfoximine-based tetrazoles have been synthesized via azido-Ugi four-component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 °C the presence InCl3. Replacement sulfoximines with sulfonimidamides (SIA) has delivered corresponding SIA-based tetrazole. Interestingly, SIA also acts as a surrogate amine to furnish aminotetrazole by-product.

BACKGROUND AND PURPOSE Size and shape of saccular intracranial aneurysms (sIA) reflect the condition of the sIA wall and were risk factors for rupture in previous follow-up studies. We investigated how well size or shape identify rupture-prone sIAs. METHODS In a population-based registry, we investigated the characteristics of ruptured sIAs treated in a single neurosurgical center (1980-2014)...

Dengue fever (DF) is the most prevalent arthropod-borne viral disease which affects humans. DF is caused by the four dengue virus (DENV) serotypes, which are transmitted to the host by the mosquito Aedes aegypti that has key roles in DENV infection, replication, and viral transmission (vector competence). Mosquito saliva also plays an important role during DENV transmission. In this study, we d...

Mechanical stretch has been demonstrated to have electrophysiological effects on cardiac muscle, including alteration of the probability of excitation, alteration of the action potential waveform, and stretch-induced arrhythmia (SIA). We demonstrate that regional ventricular ischemia due to coronary artery occlusion increases arrhythmogenic effects of transient diastolic stretch, whereas global...

Sialic acids (Sia) are widely expressed as terminal monosaccharides on eukaryotic glycoconjugates. They are involved in many cellular functions, such as cell-cell interaction and signal recognition. The key enzyme of sialic acid biosynthesis is the bifunctional UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE), which catalyses the first two steps of Sia biosynthesis in the cy...

BACKGROUND Many weight-loss programs in children are performed without specific foci on training both physical fitness and motor skills. The aim of this study was to describe the effect of a one-year weight-loss program on children's motor skills and physical fitness. METHODS Participants included 115 overweight fifth-grade children (12.0 years) randomized into either a Day-Camp Intervention ...