نتایج جستجو برای: thalassemia carrier rate
تعداد نتایج: 1042539 فیلتر نتایج به سال:
Background: Thalassemia carrier screening is a major preventive measure potentially influenced by the level of knowledge, particularly in adolescents. Therefore, this study aimed to analyze effect health education on knowledge thalassemia adolescents and its association with their willingness do screening.Methods: A cross-sectional was conducted using data regarding before after sessions from 2...
Introduction: Beta-thalassemia is characterized by absence or reduced synthesis of the β-globin. Carriers of β-thalassemia, typically have microcytic hypochromic anemia and elevated hemoglobin HbA2 and normal HbF level. On the other hand carriers of severe alpha-thalassemia also have similar CBC parameters to that of β-thalassemia with normal HbA2 level. Co-presence of mutations in the β-globin...
Background and purpose: Throughout the world 5.2% of the population is carrier for a main hemoglobin disorder. Mazandaran province in North of Iran is highly influenced by heterozygote advantage resulting in high prevalence of hemoglobinopathies. Hemoglobin E is one of the beta globin variants that can cause severe anemia such as thalassemia major. Materials and methods: This descriptive st...
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OBJECTIVES The survival rate of thalassemia patients has not been conclusively established, and the factors associated with survival remain unclear. This study aimed to determine the survival rate of thalassemia among patients in southern Iran and to identify the factors associated with mortality from thalassemia. METHODS This retrospective cohort study was conducted based on a retrospective ...
Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic individuals. The total annual incidence of symptomatic individuals is estimated at 1 in 100,000 throughout the world and 1 in 10,000 people in the European Union. Three main...
Background: According to a report of WHO in 2007, 7% world populations are carrier for Haemoglobindisorder and accurate timely detection various Hb variants including beta thalassemia trait can preventoccurrence more serious disorders like major new-borns. But developing country ususe high pressure liquid chromatography (HPLC) is limited, manual testing done assessmentis quite impossible. So, a...
Abstract Background & Objectives: Thalassemia syndromes isone of the inherited disorders in which one or more globulin chains are affected. On the basis of clinical symptoms, thalassemias are categorized as minor, intermediate, and major. Minor beta -thalassemia is a mild microcytic hypo chromic anemia in most cases asymptomatic and HbA2 is more than normal. Materials & Methods: This study carr...
Thalassemia is among the most common genetic disorders worldwide; 4.83 percent of the world’s population carry globin variants, including 1.67 percent of the population who are heterozygous for a -thalassemia and b -thalassemia. In addition, 1.92 percent carry sickle hemoglobin, 0.95 percent carry hemoglobin E, and 0.29 percent carry hemoglobin C. Thus, the worldwide birth rate of people who ar...
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