Objectives. This study aimed to explore the effect and mechanism of Yangjing capsule on testosterone secretion in mouse Leydig tumor cells (MLTC-1). Methods. MLTC-1 cells were treated with the Yangjing capsule extract for 24 h. The testosterone level in medium was measured by radioimmunoassay. The expression of steroidogenic enzymes (StAR, CYP11A1, and HSD3B) in the cells was examined using rea...

Zinc deficiency is prevalent throughout the world, including the USA. Severe and moderate deficiency of zinc is associated with hypogonadism in men. However, the effect of marginal zinc deficiency on serum testosterone concentration is not known. We studied the relationship between cellular zinc concentrations and serum testosterone cross-sectionally in 40 normal men, 20 to 80 y of age. In four...

s:1080:"Background: Studies have shown that gasoline vapor influences many physiological aspects of body. The present study was exerted to evaluate the effects of gasoline vapor inhalation on serum levels of testosterone in male rats. Materials and Methods: Male Wistar rats were randomly divided into control, gasoline vapor receiving for 1hour, 2 hours and 3 hours/day. After 10 weeks, blood sam...

objective: to evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. materials and methods: in this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. the two groups were matched for their age and bmi. after complete observation and examination, ...

background:   objective: the aim of this study was to investigate the effects of aqueous and hydro-alcoholic extracts of lettuce seed on testosterone level and spermatogenesis.   materials and methods: in this experimental study 24 adult male nmri mice weighing 20-25gr were purchased. animals were randomly divided into 4 groups: controls, hydro-alcoholic (200 mg/kg) and aqueous extracts (50, 10...

Recent developments in the field of mass spectrometry have provided the accuracy and sensitivity to evaluate very-low-abundance steroids such as testosterone in female and pediatric patients. In this issue of Clinical Chemistry, Taieb et al. (1 ) present the most comprehensive evaluation of automated testosterone immunoassays to date. They compared 10 commercially available immunoassays with is...

Salivary testosterone levels in Korean adults were quantitatively measured for the first time by liquid chromatography-electrospray-tandem mass spectrometry (LC ESI MS/MS). Salivary testosterone was separated on a multiple reaction monitoring (MRM) chromatogram within 7 min. The LC ESI MS/MS assay was validated over the linearity range of 0.01-2.00 ng/ml (r=0.99987) using testosterone-d(3) as a...

The present study was aimed to assess the potential of infertility to induce the adverse effects with reference to testosterone, Triiodothyronine (T3), Thyroxine (T4), Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), zinc, copper and iron. All the samples were divided into four groups according to age and disorder (Group 1, 10 infertile men of 25 40 years; Group 2, 10 fertile m...

PURPOSE Late-onset hypogonadism (LOH) in aging males is a clinical and biochemical syndrome characterized by a decline in serum testosterone levels. LOH results in various physical and mental disabilities. We evaluated the relationship between serum testosterone levels and symptoms of LOH. MATERIALS AND METHODS During an andropause screening program, we examined responses to the Saint Louis u...

BACKGROUND Spinal cord injury (SCI) causes infertility in male patients through erectile dysfunction, ejaculatory dysfunction, semen and hormone abnormalities. Oxidative stress (OS) is involved in poor semen quality and subsequent infertility in males with SCI. The aim of this study is to examine the effects of SCI on the level of testosterone hormone. MATERIALS AND METHODS In this experiment...