Epithelial cell appearance and cell size were studied in intact, unfixed, and unstained human lenses. Ten normal and 24 cryoextracted senile or presenile cataractous lenses, all with subcapsular cataract, were examined. The cell size of the transparent normal lenses showed little variation. However, in the cataractous lenses, a wide range was found in mean cell size of different lenses and vari...

This study presents a simple but sensitive HPLC chromatographic method with a stability-indicating assay for determination and physicochemical characterisation of L-carnosine, a promising senile cataract prophylactic agent. Chromatographic analysis was conducted using a reverse phase (RP)-HPLC system and an isocratic mobile phase of 98% v/v trifluoroacetic acid (0.1% v/v) and 2% v/v acetonitril...

A solitary report in the literature suggests that determination of phosphohexose isomerase (PHI; glucosephosphate isomerase, EC 5.3.1.9) activity in aqueous humor and serum may be a useful adjunct in the diagnosis f retinoblastoma (1). The aqueous humor/serum PHI ratio of 20 patients with retinoblastoma was compared with that for eight “controls” having intraocular diseases other than retinobla...

purpose : to determine the incidence and determinants of intraoperative complications of cataract surgeries performed in iran during 2000 to 2005 methods : the iranian cataract surgery survey (icss) is a retrospective study in which random sampling was done from selected centers. one week per season between 2000 and 2005 was assigned to each center and records of cataract surgeries performed du...

PURPOSE To identify the main causes of visual impairment (VA <or= 0.2) within the population over 50 years of age examined in "Cataract Free Zone" projects sponsored by the University of Campinas from 1986 to 1995. METHODS A retrospective review of the ophthalmic forms used for 60,404 patients examined in 74 Cataract Projects was performed. Through mass media information, adults of the target...

To evaluate the level of glutathione (GSH) and gluthathione peroxidase (GSH-Px) activity in the anterior ule of patients with cataract in diabetic patients with meticulous control and in patients with senile cataract. The anterior lens capsules in 18 eyes with diabetes under tight glycemic control with cataract (Group A) 6 eyes with senile cataract (Group B) were collected in phacoemulsificatio...

The pathogenesis of cataract is associated with oxidative stress and with altered crystallin expression but it is still understood incompletely. In this study, the senescence-accelerated OXYS rats were used as a model. The first biomicroscopic signs of cataract in OXYS rats were registered at the age of 1.5 months; at 3 months morbidity reached 90%, and at 6 months it reached 100%. Cataract man...

AIM To find out the incidence of primary posterior capsular opacification (PCO) in rural patients with a hypermature senile cataract undergoing cataract surgery. SETTINGS Tertiary eye care center in central India. DESIGN Prospective, observational, noncomparative study. MATERIALS AND METHODS Two-hundred eyes of 200 patients presenting with a hypermature cataract underwent manual small inc...