BACKGROUND Skin autofluorescence (SAF) is a noninvasive marker of advanced glycation end products (AGEs). In diabetes, higher SAF levels have been positively associated with long-term complications, cardiovascular morbidity and mortality. Because little is known about the factors that influence SAF in nondiabetic individuals, we assessed the association of clinical and lifestyle parameters with...

A dvanced glycation end product (AGE) burden can be indirectly quantified in vivo by measuring skin autofluorescence (SAF) (1). It has been recently published by Felipe et al. (2) that SAF is correlated with glycated he-moglobin (GHb) but not with mean blood glucose (MBG) in type 1 diabetic children. This suggests that factors besides MBG exposure may be influential in skin AGE generation. In t...

Objectives: The aim of the present study was to investigate immunotoxic effect of safranal (SAF), a main component of Crocus sativus essential oil, using Balb/c mice. Materials and Methods: SAF was administered intraperitoneally at doses of 0.1, 0.5 and 1 ml/kg for 3 weeks. Hystopathological examination of spleen and bone marrow, cellularity of spleen, delayed type of hypersensitivity (DTH) res...

AIM Diabetes (DM) and impaired glucose tolerance (IGT) detection are conventionally based on glycemic criteria. Skin autofluorescence (SAF) is a noninvasive proxy of tissue accumulation of advanced glycation endproducts (AGE) which are considered to be a carrier of glycometabolic memory. We compared SAF and a SAF-based decision tree (SAF-DM) with fasting plasma glucose (FPG) and HbA1c, and addi...

Forced hydraulic jump in a horizontal stilling basin with one and two continuous sills at the downstream end of an ogee standard weir was investigated. Experiments were completed on sills of five different heights which were fixed at two different distances from the toe of the weir. The main characteristics of the jump such as the sequent depth ratio, relative roller &#10length, and relative en...

Abundantly expressed serum amyloid A (SAA) protein under chronic inflammatory conditions gives rise to insoluble aggregates of SAA derivatives in multiple organs resulting in reactive amyloid A (AA) amyloidosis, a consequence of rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, familial Mediterranean fever, and Castleman's disease. An inflammation-responsive transcription factor, S...

Block ramps are hydraulic structures which are commonly used in river restoration projects. Especially in the last few decades, the use of this type of structures have become more and more popular. They furnish a correct balance between the hydraulic functioning and the environmental care, as they minimize the impact on the environment in which they are located. In addition, they can be conside...

The adaptation of existing dams is paramount importance to face the challenge posed by climate change and new legal frameworks. Thus, it crucial optimize design stilling basins reduce hydraulic jump dimensions without jeopardizing energy dissipation in structure. A numerical model was developed simulate a US Bureau Reclamation Type II basin. validated with specifically designed physical then us...

Midlatitude mountain regions are particularly sensitive to climate change because of an active snow albedo feedback (SAF). Here, the SAF is characterized and quantified over the complex terrain of the Colorado Headwaters region using high-resolution regional climate model simulations. A pair of 7-yr control and pseudo-global warming simulations is used to study the regional climate response to ...