نتایج جستجو برای: rhomboid domain containing 1
تعداد نتایج: 3282829 فیلتر نتایج به سال:
Clathrin-mediated endocytosis (CME) is facilitated by a precisely regulated burst of actin assembly. PtdIns(4,5)P2 is an important signaling lipid with conserved roles in CME and actin assembly regulation. Rhomboid family multipass transmembrane proteins regulate diverse cellular processes; however, rhomboid-mediated CME regulation has not been described. We report that yeast lacking the rhombo...
We report the case of a 28-year-old transgender (male-to-female) patient that had a partial tear of the rhomboid major tendon, scapulothoracic bursitis, and glenohumeral instability on the same side. These conditions resulted from traumatic events during circus acrobatic maneuvers. Additional aspects of this case that make it unique include (1) the main traumatic event occurred during a flagpol...
Cytoplasmic linker protein (CLIP)-170 is a microtubule (MT) plus-end-tracking protein that regulates MT dynamics and links MT plus ends to different intracellular structures. We have shown previously that intramolecular association between the N and C termini results in autoinhibition of CLIP-170, thus altering its binding to MTs and the dynactin subunit p150(Glued) (J. Cell Biol. 2004: 166, 10...
Rhomboid flaps are frequently used in facial reconstruction to repair rhombus-shaped defects. The aesthetic and mechanical properties of these flaps make them especially useful for reconstruction of defects on the cheek, temple, lips, nose, and eyelids. Rhomboid flaps are full-thickness cutaneous local flaps with a random blood supply; they rely on the dermal–subdermal plexus of blood vessels. ...
OBJECTIVE The aim of this study is to present our clinical experience with rhomboid flaps. MATERIALS AND METHODS Twenty-four patients who were operated on between January 2006 and October 2010 were included in the study. All defects were reconstructed using rhomboid flaps. RESULTS Twenty-four patients were operated on for various reasons, and 26 rhomboid flaps were performed. Eleven of the ...
CLIP-170/Restin belongs to a family of conserved microtubule (MT)-associated proteins, which are important for MT organization and functions. CLIP-170 is a phosphoprotein and phosphorylation is thought to regulate the binding of CLIP-170 to MTs. However, little is known about the kinase(s) involved. In this study, we show that FKBP12-rapamycin-associated protein (FRAP, also called mTOR/RAFT) in...
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