نتایج جستجو برای: recombinant protein sag1

تعداد نتایج: 1297381  

Journal: :iranian journal of blood and cancer 0
mehryar habibi roudkenar mahshid mohammadipour arezou oodi raheleh halabian naser amirizadeh nasser masrouri

background: the rh antigens are expressed as parts of a protein complex in the rbc membrane. this complex is a tetramer, consisting of two molecules of rhag and two molecules of rh proteins. to express rhd in rbc membrane, expression of rhag is essential. this co-expression only occurs in the erythroid lineage. k562 cell line has an erythroid lineage. materials and methods: cord blood was used ...

Journal: :iranian journal of biotechnology 2008
seyed abbas shojaosadati seyedeh marjan varedi kolaei valiollah babaeipour amir mohammad farnoud

this paper reviews recent strategies used for increasing specific yield and productivity in high cell density cultures. high cell density cultures offer an efficient means for the economical production of recombinant proteins. however, there are still some challenges associated with high cell density cultivation (hcdc) techniques. a variety of strategies in several aspects including host design...

Journal: :iranian journal of basic medical sciences 0
roghayeh rahimi department of immunology, faculty of medical sciences, tarbiat modares university, tehran , iran massoumeh ebtekar department of immunology, faculty of medical sciences, tarbiat modares university, tehran , iran seyed mohammad moazzeni department of immunology, faculty of medical sciences, tarbiat modares university, tehran , iran ali mostafaie biotechnology research center, kermanshah university, kermanshah, iran mehdi mahdavi department of virology, pasteur institute of iran, tehran, iran

objective(s):multi-epitopic protein vaccines and direction of vaccine delivery to dendritic cells (dcs) are promising approaches for enhancing immune responses against mutable pathogens. escherichia coli is current host for expression of recombinant proteins, and it is important to optimize expression condition. the aim of this study was the optimization of multi-epitopic hiv-1 tat/pol/gag/env ...

Journal: :iranian journal of parasitology 0
p shahbazi p shayan e ebrahimzadeh s rahbari

background: cryptosporidium parvum is a parasitic protozoan that functions as important causa­tive agent of diarrhea in human and animals. the host's immune response to surface anti­gens of c. parvum has been previously demonstrated. in this respect, the role of humoral immu­nity in the development of host protective immunity against this protozoon has been well demon­strated. methods: the effe...

Journal: :iranian journal of basic medical sciences 0
hossein fahimi department of genetics, faculty of biological sciences, tarbiat modares university, tehran, iran 2 department of cellular and molecular biology, islamic azad university, pharmaceutical sciences branch (iaups), tehran, iran hossein allahyari department of immunology, faculty of medical sciences, tehran medical university, tehran, iran zuhair m hassan department of immunology, faculty of medical sciences, tarbiat modares university, tehran, iran majid sadeghizadeh department of genetics, faculty of biological sciences, tarbiat modares university, tehran, iran

objective(s): production of a recombinant and immunogenic antigen using dengue virus type-3 envelope protein is a key point in dengue vaccine development and diagnostic researches. the goals of this study were providing a recombinant protein from dengue virus type-3 envelope protein and evaluation of its immunogenicity in mice. materials and methods: multiple amino acid sequences of different i...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Dietlind L Gerloff Alison Creasey Siarhei Maslau Richard Carter

Ps230 is the largest representative of a 10-member family of proteins found in all Plasmodium species. The family is defined by partially conserved, cysteine-rich double domains that are approximately 350 aa in length and have one to three predicted disulfide bridges in each half. In Plasmodium falciparum, the most dangerous human malaria, Pf12 is the smallest member of the family, comprising j...

Journal: :iranian journal of pharmaceutical research 0
hamid reza heidari department of pharmaceutical biotechnology, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran mojgan bandehpour cellular and molecular biology research center, shahid beheshti university of medical sciences, tehran, iran department of biotechnology, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran hossein vahidi department of pharmaceutical biotechnology, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran jaleh barar research centre for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran bahram kazemi shahid beheshti university of medical sciences hossein naderi-manesh department of biophysics, faculty of biological sciences, tarbiat modares university, tehran, iran

molecular farming has been considered as a secure and economical approach for production of biopharmaceuticals. human tnf related apoptosis inducing ligand (trail) as a promising biopharmaceutical candidate has been produced in different expression hosts. however, little attention has been paid to molecular farming of the trail in spite of numerous advantages of plant expression systems. theref...

Journal: :archives of clinical infectious diseases 0
mojgan bandehpour cellular and molecular biology research center, shahid beheshti university, m.c., tehran, ir iran narges abdali islamic azad university, research and science campus, tehran, ir iran farzaneh sadeghi department of biology, shahid beheshti university, m.c., tehran, ir iran kazem parivar islamic azad university, research and science campus, tehran, ir iran zarrin sharifnia cellular and molecular biology research center, shahid beheshti university, m.c., tehran, ir iran hossein ryahi department of biology, shahid beheshti university, m.c., tehran, ir iran

background brucellosis is an important cosmopolitan infection disease caused by organisms belonging to the genus brucella. the cgt gene (cyclic β-1, 2 glucan transporter gene) is a virulent factor in brucella genus. the present study was conducted with the aim of cloning and expression of brucella cgt gene. materials and methods brucella melitensis cgt gene was amplified from extracted chromoso...

زیبایی, سعید, حق‌پرست, ، علیرضا , دوستی, محمد , طهمورث‌پور, مجتبی , نصیری, ، محمدرضا ,

     Foot-and-mouth disease (FMD) is an extremely infectious and occasionally fatal viral disease with a rapid onset and a short course that affects cloven-hoofed animals and results in considerable financial losses. For this reason, availability of more reliable and efficient vaccines against Foot-and-mouth disease virus (FMDV) is felt as a necessity. The purpose of this study is to develop a ...

Journal: :iranian biomedical journal 0
مصیب رستمیان mosayeb rostamian سید جعفر موسوی seyed jafar mousavy فیروز ابراهیمی firouz ebrahimi سید ابوالقاسم قدمی seyyed abolghasem ghadami نادر شیبانی nader sheibani محمد ابراهیم مینایی mohammad ebrahim minaei محمد علی عارف پور ترابی

background: recently, botulinum neurotoxin (bont)-derived recombinant proteins have been suggested as potential botulism vaccines. here, with concentrating on bont type e (bont/e), we studied two of these binding domain-based recombinant proteins: a multivalent chimer protein, which is composed of bont serotypes a, b and e binding subdomains, and a monovalent recombinant protein, which contains...

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