a flow injection method is reported for the determination of ascorbic acid based on amperometric detection, using a cobalt(ii) phthalocyanine (copc) modified graphite-epoxy electrode. the amperometric respons was evaluated with regard to ph, ionic strength of the electrolyte, flow rate of the carrier solution, injected sample volume and conditioning time of the electrode. the limit of detection...

A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of Zolpidem tartrate in bulk and pharmaceutical dosage forms. Zolpidem tartrate shows maximum absorbance at 238.5 nm with molar absorptivity of 4.4648×10lit/mol/cm. Beer’s law was obeyed in the concentration range of 2-16 μg/ml. The limit of detection and limit of quantification were...

a simple and reliable electrochemical sensor based on cobalt oxide nanoparticles modified glassy carbon electrode (gce/cooxnps) for determination of butylated hydroxyanisole is presented here. the nanoparticles were fabricated by electrodepositing method. the modified electrode shows excellent catalytic activity toward butylated hydroxyanisole oxidation in ph 12.0 phosphate buffer solution (pbs...

Kohlenbach’s proof mining program deals with the extraction of effective information from typically ineffective proofs. Proof mining has its roots in Kreisel’s pioneering work on the so-called unwinding of proofs. The proof mining of classical mathematics is rather restricted in scope due to the existence of sentences without computational content which are provable from the law of excluded mid...

In this paper, we show how to analyze bifurcation and limit cycles for biological systems by using an algebraic approach based on triangular decomposition, Gröbner bases, discriminant varieties, real solution classification, and quantifier elimination by partial CAD. The analysis of bifurcation and limit cycles for a concrete two-dimensional system, the self-assembling micelle system with chemi...

One of the goals of computability theory is to find syntactic equivalences for computational properties. The Limit Lemma is a classic example of this type of equivalence: X ⊆ ω is computable from 0′ if and only if it is arithmetically definable by a ∆2 formula. A more relevant example for this paper was proved independently by Ash, Knight, Manasse and Slaman [1] and by Chishom [2]: a computable...

1 Uncertain knowledge can be modeled by using graded probabilities rather than binary truth-values, but so far a completely satisfactory integration of logic and probability has been lacking. In particular the inability of confirming universal hypotheses has plagued most if not all systems so far. We address this problem head on. The main technical problem to be discussed is the following: Give...

The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 2...

A simple and sensitive method for the simultaneous determination of ethanol, ethyl acetate, tetrahydrofuran, 2-propanol, hexane, dichloromethane and methanol in five drug substances by headspace techniques with FID detection is described. The method was validated for repeatability, linearity, limit of detection, limit of quantification and recovery according to the International Conference on H...

A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in the concentration range of 1.5-18 μg/ml. The limit of detection and limit of quantification were found t...