نتایج جستجو برای: proinflammatory

تعداد نتایج: 25298  

Journal: :American journal of physiology. Heart and circulatory physiology 2002
Sakuji Shigematsu Shuji Ishida Dean C Gute Ronald J Korthuis

Intravital microscopic techniques were used to examine the mechanisms underlying bradykinin-induced leukocyte/endothelial cell adhesive interactions (LECA) and venular protein leakage (VPL) in single postcapillary venules of the rat mesentery. The effects of bradykinin superfusion to increase LECA and VPL were prevented by coincident topical application of either a bradykinin-B(2) receptor anta...

Journal: :Physiological research 2009
R Poledne A Lorenzová P Stávek Z Valenta J Hubácek P Suchánek J Pitha

Over the last decade, C-reactive protein concentration analyzed by the high sensitivity method (hsCRP) has been proven as a marker of premature atherosclerosis. Concentration exceeding 2 mg/l represents an increased individual risk of myocardial infarction and stroke but strict application of this borderline is complicated by relations of CRP concentrations to other risk factors of cardiovascul...

2011
Adrian C. Hayday Brian J. Nickoloff Frank O. Nestle Catherine H. Smith Ute Laggner Paola Di Meglio Gayathri K. Perera Christian Hundhausen Katie E. Lacy

gd T cells mediate rapid tissue responses in murine skin and participate in cutaneous immune regulation including protection against cancer. The role of human gd cells in cutaneous homeostasis and pathology is characterized poorly. In this study, we show in vivo evidence that human blood contains a distinct subset of proinflammatory cutaneous lymphocyte Ag and CCR6-positive Vg9Vd2 T cells, whic...

2018
Junfei Jin Zhongyang Lu Yanchun Li L Ashley Cowart Maria F Lopes-Virella Yan Huang

It is well known that saturated fatty acids (SFAs) and unsaturated fatty acid, in particular omega-3 polyunsaturated fatty acids (n-3 PUFAs), have different effects on inflammatory signaling: SFAs are pro-inflammatory but n-3 PUFAs have strong anti-inflammatory properties. We have reported that palmitic acid (PA), a saturated fatty acid, robustly amplifies lipopolysaccharide (LPS) signaling to ...

Journal: :American Journal of Respiratory Cell and Molecular Biology 2013

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