نتایج جستجو برای: prevalent cancers
تعداد نتایج: 159263 فیلتر نتایج به سال:
Background: Urological care has been advancing quickly over the last ten years in Benin. In order to conveniently support that trend towards better urological standards, decision-makers need sound data on diseases country. Objective: To determine prevalence of former Military Teaching Hospital Cotonou. Patients and Method: We retrospectively collected institution had managed from January 2012 D...
Arsenic, a toxic metalloid, provokes many detrimental consequences to human health. It is prevalent in earth’s crust and poses major threat humans globally. Inorganic arsenic exposure occurs mainly via drinking water or food metabolized mammals form organic metabolites/ end products. Chronic causes lung, skin urinary bladder cancers increases the risks of liver, kidney prostate cancers. Arsenic...
Enhancer of zeste homolog 2 (EZH2) is a candidate oncogenic driver due to its prevalent overexpression and aberrant repression of tumor suppressor genes in diverse cancers. Therefore, blocking EZH2 enzyme activity may present a valid therapeutic strategy for the treatment of cancers with EZH2 overexpression including breast cancers. Here, we described ZLD1039 a potent, highly selective, and ora...
Patients with the acquired immunodeficiency syndrome are at risk to develop a variety of different cancers. Based on epidemiolÃ3gica! data, Kaposi's sarcoma and non-Hodgkin's lymphoma have been clearly asso ciated with infection by the human immunodeficiency virus (HIV). Ad ditional cancers such as basal cell and squamous cell carcinomas, mela noma, and hepatocellular carcinoma have also been r...
Immunoglobulins (Igs) are found thus far only to be produced by differentiated B lymphocytes. By immunohistochemistry analysis, in situ hybridization, and laser capture microdissection-assisted single-cell PCR, we demonstrate that human cancers of epithelial origin, including carcinomas of breast, colon, liver, lung, established epithelial cancer lines, as well as some normal lung tissues, also...
Cancer cells rely on telomerase or the alternative lengthening of telomeres (ALT) pathway to overcome replicative mortality. ALT is mediated by recombination and is prevalent in a subset of human cancers, yet whether it can be exploited therapeutically remains unknown. Loss of the chromatin-remodeling protein ATRX associates with ALT in cancers. Here, we show that ATRX loss compromises cell-cyc...
Background: Hematuria, characterized by red blood cells in the urine, is a clinical symptom that demands an immediate investigation for potential urologic cancers, particularly cases of gross hematuria. This study seeks to comprehensively review various malignancies causing hematuria, such as urothelial carcinoma, renal cell and prostate ductal carcinoma. The anchored on current guidelines publ...
Abstract Background Skin cancers are among the widely prevalent forms of cancer worldwide. The increasing industrialization and accompanied environmental changes have further worsened skin statistics. stern topical barrier although difficult to breach is a little compromised in pathologies like cancer. therapeutic management has moved beyond chemotherapy surgery. Main body abstract quest for ma...
background non-melanoma skin cancers (nmsc) are the most common cancers worldwide. these cancers are not accompanied by high mortality however they lead to various complications. evaluation of nmsc predisposing factors could result in preventive measures, improvement of quality of life and reduction of medical costs. objectives this study aimed to determine predisposing factors of non-melanoma ...
background: the induction of cancer appears to be the most important effect of low-dose ionizing radiation to occur in an exposed population. in developing countries 94% of human radiation is from natural sources. in iran some high altitude regions such as, chaharmahal & bakhtiari has high levels of the natural background radiation (higher than the worldwide average). therefore, investigation o...
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