Ecstasy users have previously reported subjective problems with sleep following use [1, 2], and laboratory studies have demonstrated altered sleep architecture in ecstasy users [3]. The current study examined whether ecstasy contributed to sleep disturbance to a clinically significant level in users in the presence or absence of polydrug use, and determined the extent to which the amount or fre...

This paper studies polydrug use patterns in heroin and cocaine addicts. We use data on two experiments to measure the elasticity of several addictive drugs with respect to heroin and cocaine prices. Own and cross price elasticities are estimated while controlling for non-price related sources of variance. The results indicate that heroin addicts have an inelastic demand for heroin, complement h...

Rationale/Objectives: Recent theoretical models suggest that the central executive may not be a unified structure. The present study explored the nature of central executive deficits in ecstasy users. Methods: In Study One, 27 ecstasy users and 34 nonusers were assessed using tasks to tap memory updating (computation span; letter updating) and access to long-term memory (a semantic fluency test...

Fluorescent microspheres (FM) have become an attractive alternative to radioactive microspheres (RM) for the measurement of regional blood flow (RBF). The aim of the present study was to investigate the comparability of both methods by measuring RBF with FM and RM. Eight anaesthetised pigs received simultaneous, left atrial injections of FM and RM with a diameter of 15 microm at six different t...

Regular ecstasy users show significantly higher levels of self-rated paranoid ideation (SCL-90-R) relative to matched controls [2]. However, regular ecstasy consumers are typically polydrug users and there is evidence that psychopathological symptoms experienced by this group are more strongly associated with the use of other substances, such as cannabis, rather than being solely reflective of ...