The dynamics of active entangled chains using molecular simulations a modified Kremer–Grest model. are diluted in mesh very long passive linear chains, to avoid constraint release effects, and an force is applied the monomers way that it imparts constant polar drift velocity along primitive path. simulation results show that, over wide range activity values, conformational properties tubes not ...

Electro-Fluidic Displays (EFD) have been demonstrated to be an attractive technology for incorporation into portable display devices. EFDs have excellent optical efficiency and fast switching enabling video content. Ensuring mechanical stability of EFD display cells is a key challenge and essential for developing large area as well as flexible displays. Although the electro-optic performance of...

The problem of describing a protein representation by breaking up the amino acids atoms into functionally similar atom groups has been addressed by many researchers in the past 25 years. They have used a variety of physical, chemical and biological criteria of varying degrees of rigor to essentially impose our understanding of protein structures onto various atom-typing schemes used in studies ...

BACKGROUND Vancomycin and related glycopeptide antibiotics exert their antimicrobial effect by binding to carboxy-terminal peptide targets in the bacterial cell wall and preventing the biosynthesis of peptidoglycan. Bacteria can resist the action of these agents by replacing the peptide targets with depsipeptides. Rational efforts to design new agents effective against resistant bacteria requir...

We demonstrate that therapeutically useful amounts of insulin are absorbed by the nasal mucosa of human beings when administered as a nasal spray with the common bile salts. By employing a series of bile salts with subtle differences in the number, position, and orientation of their nuclear hydroxyl functions and alterations in side chain conjugation, we show that adjuvant potency for nasal ins...

In polar aprotic organic solvents, fluorine might be an element of choice for life that uses selected fluorinated building blocks as monomers of choice for self-assembling of its catalytic polymers. Organofluorine compounds are extremely rare in the chemistry of life as we know it. Biomolecules, when fluorinated such as peptides or proteins, exhibit a "fluorous effect", i.e., they are fluorophi...

The opportunistic pathogen Pseudomonas aeruginosa produces multifunctional, polar, filamentous appendages termed type IV pili. Type IV pili are involved in colonization during infection, twitching motility, biofilm formation, bacteriophage infection, and natural transformation. Electrostatic surface analysis of modeled pilus fibers generated from P. aeruginosa strain PAK, K122-4, and KB-7 pilin...

The reactor used to destroy and modify polyisobutylene in the laboratory has been made of pyrex glass. For first time, Friedel-Crafts catalysts were found be initiators a radical chain-chain mechanism for destruction polyisobutylene. Based on this mechanism, it modified with polar monomers (acrylonitrile vinilacetate). This creates conditions production new types copolymers. At same participati...

A bis(squaraine) dye equipped with alkyl and oligoethyleneglycol chains was synthesized by connecting two dicyanomethylene substituted squaraine dyes a phenylene spacer unit. The aggregation behavior of this investigated in non-polar toluene/tetrachloroethane (98:2) solvent mixture, which revealed competing cooperative self-assembly pathways into supramolecular polymorphs entirely different pac...