We have investigated the effects of tyrosine nitration (to form the weak acid, 3-nitrotyrosine) at positions 23 or 20 plus 23, on the structure and function of hen egg-white lysozyme. Enzyme activity against Micrococcus luteus cell-wall fragments or soluble substrates exhibits two phenomena. (a) A decrease in Km and kcat for the hydrolysis of soluble oligo- and poly-saccharides, resulting in on...

A minor-closed class of graphs is a set of labelled graphs which is closed under isomorphism and under taking minors. For a minor-closed class G, we let gn be the number of graphs in G which have n vertices. A recent result of Norine et al. [12] shows that for all minor-closed class G, there is a constant c such that gn ≤ c nn!. Our main results show that the growth rate of gn is far from arbit...

Background and Aim: There is lack of information regarding the effect of different denture cleansing solutions on the retention of attachments. This study aimed to as-sess the effect of denture cleansing solutions on the retention of Dalbo-Plus and Loca-tor attachment systems. Materials and Methods: This study evaluated 160 attachments including 80 Locator and 80 Dalbo-Plus attachment systems....

Researchers have recently investigated the efficacy of different strategies for recovering from service failure. This paper reports two studies that test the effects of a reactive recovery strategy (compensation) and a proactive strategy (establishing prior rapport between service provider and customer). These strategies, plus aspects of the service problem, were manipulated using written scena...

Antitumor necrosis factor therapies have revolutionized the treatment of some inflammatory diseases. However, the use of these agents is associated with the development of many paradoxical autoimmune diseases. Less well-recognized is the association with sarcoidosis. We report a 55-year-old female with long-standing ankylosing spondylitis who developed persistent dry cough and dyspnea while rec...

In a double-blind, placebo controlled and randomised secretory study the effectiveness of pirenzepine, ranitidine, and their combination was compared intraindividually in eight healthy subjects receiving intravenous bolus injections. Pirenzepine (0.15 mg/kg) plus ranitidine (0.6 mg/kg) suppressed peptone-stimulated gastric acid secretion from 69 +/- 11 to 2 +/- 0.4 mmol H+/3 h; the mean percent...