نتایج جستجو برای: paraquat dichloride

تعداد نتایج: 5267  

2011
Myles Cockburn Paul Mills Xinbo Zhang John Zadnick Dan Goldberg Beate Ritz

In a population-based case-control study in California’s intensely agricultural Central Valley (2005–2006), the authors investigated relations between environmental pesticide/fungicide exposure and prostate cancer. Cases (n 1⁄4 173) were obtained from a population-based cancer registry, and controls (n 1⁄4 162) were obtained from Medicare listings and tax assessor mailings. Past ambient exposur...

Journal: :British journal of industrial medicine 1981
J K Howard N N Sabapathy P A Whitehead

Tests of pulmonary function (FVC, FEV1, FEV 1%, and single breath CO diffusion), renal function (serum creatinine and BUN), liver function (serum ALT, AST, and ALKP) and a full haematological screen were performed on 27 paraquat spraymen (mean spraying time 5.3 years; mean individual annual quantity of paraquat handled, 67.2 kg as paraquat ion) and on two control groups. One of the control grou...

Ali Mohammad Sabzghabaee Arman Otroshi Nastaran Eizadi-Mood,

Dear editor, We read the recent article of Rahmani et al entitled "Medical Management and Outcome of Paraquat Poisoning in Ahvaz, Iran: A Hospital-Based Study" in your journal (1). In their study they performed upper gastrointestinal (GI) endoscopy as a routine for all paraquat poisoned patients, because they considered paraquat a caustic agent and that it may cause severe mucosal injuries in e...

2017
VALENTINA N. GLUSHkO

Study of interaction between catechol and tetraethylene glycol dichloride in the n-butanol media, resulting with benzo-15-crown-5 production. Production of nitroand amino-derivatives of benzo-15-crown-5. Determination of their thermogravimetric characteristics. keywords: benzo-15-crown-5, catechol, tetraethylene glycol dichloride, crown ether, gas liquid chromatography, chromate-mass spectrometry

2009
Kwon-Hyun Lee Hyo-Wook GIL Young-Tong Kim Jong-Oh Yang Eun-Young Lee Sae-Yong Hong

BACKGROUND/AIMS Paraquat-induced lung injury has been considered a progressive and irreversible disease. The purpose of this study was to report the long-term evolution of lung lesions in eight survivors with significant paraquat-induced lung injuries who could be followed-up for longer than 6 months. METHODS We retrospectively examined high-resolution computed tomography and pulmonary functi...

2017
Chris A. Rudyk Jessica McNeill Natalie Prowse Zach Dwyer Kyle Farmer Darcy Litteljohn Warren Caldwell Shawn Hayley

Little is known of the age-dependent and long-term consequences of low exposure levels of the herbicide and dopaminergic toxicant, paraquat. Thus, we assessed the dose-dependent effects of paraquat using a typical short-term (3 week) exposure procedure, followed by an assessment of the effects of chronic (16 weeks) exposure to a very low dose (1/10th of what previously induced dopaminergic neur...

Journal: :Synapse 2007
P O Fernagut C B Hutson S M Fleming N A Tetreaut J Salcedo E Masliah M F Chesselet

Genetic variability in the alpha-synuclein gene and long-term exposure to the pesticide paraquat constitute possible risk factors for sporadic Parkinson's disease. The goal of the present study was to further characterize the effects of paraquat in mice as a model of Parkinson's disease and to determine whether it acted synergistically with alpha-synuclein over-expression to cause nigrostriatal...

2016
Shuanghu Wang Lijing Zhang Xianqin Wang Zhiyi Wang Congcong Wen Jianshe Ma Zhimou Gao Lufeng Hu

Paraquat is one of the most widely used herbicides in the world and is highly toxic to humans and animals. Respiratory failure as a result of lung injury is the most common cause of death from paraquat. In this study, we developed a lung metabolomic method by gas chromatography-mass spectrometry (GC-MS) to evaluate the effect of acute paraquat poisoning on rats. The acute paraquat poisoning gro...

2016
A. J. Case D. Agraz I. M. Ahmad M. C. Zimmerman

Herbicides containing paraquat may contribute to the pathogenesis of neurodegenerative disorders such as Parkinson's disease. Paraquat induces reactive oxygen species-mediated apoptosis in neurons, which is a primary mechanism behind its toxicity. We sought to test the effectiveness of a commercially available polyphenol-rich Aronia melanocarpa (aronia berry) concentrate in the amelioration of ...

Journal: :Nature chemical biology 2017
Colleen R Reczek Kıvanç Birsoy Hyewon Kong Inmaculada Martínez-Reyes Tim Wang Peng Gao David M Sabatini Navdeep S Chandel

Paraquat, a herbicide linked to Parkinson's disease, generates reactive oxygen species (ROS), which causes cell death. Because the source of paraquat-induced ROS production remains unknown, we conducted a CRISPR-based positive-selection screen to identify metabolic genes essential for paraquat-induced cell death. Our screen uncovered three genes, POR (cytochrome P450 oxidoreductase), ATP7A (cop...

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