Pancreatic serous cystic neoplasms are rare lesions accounting for approximately 16% of primary cystic pancreatic neoplasms [1]. These lesions are now encountered with greater frequency due to increased availability and use of high-resolution imaging such as multi-detector computed tomography (MDCT), magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP), and are often incident...

IMPORTANCE Central pancreatectomy, as an alternative to standard resection for benign and low-grade pancreatic neoplasms, has been described in mainly small retrospective series. OBJECTIVE To describe a large single-center experience with central pancreatectomy. DESIGN, SETTING, AND PARTICIPANTS A retrospective case series in a tertiary referral center included 100 consecutive patients unde...

Although the exact prevalence of cystic pancreatic lesions is unknown, it is estimated to be around 1% of the general population based on large scale observational imaging studies [1]. While cystic pancreatic lesions are increasingly diagnosed due to the widespread use of cross-sectional imaging modalities like computed tomography (CT) and magnetic resonance imaging (MRI), it is not known if th...

This is a state-of-the-art review of the molecular genetics of pancreatic neoplasms. Although understanding of the molecular features underlying pancreatic neoplasms is still in its infancy, a strong emphasis on the relevance of these findings for the practicing surgical pathologist is provided. The application of molecular techniques has yielded a wealth of information that may soon enhance di...

The pancreas is a site of origin of a diverse range of benign and malignant tumours, and these are frequently detected, diagnosed and staged with computed tomography (CT). Knowledge of the typical appearance of these neoplasms as well as the features of locoregional invasion is fundamental for all general and abdominal radiologists. This pictorial essay aims to outline the characteristic CT app...

PURPOSE Patients with pancreatic ductal adenocarcinoma usually present with advanced-stage disease and a dismal prognosis. One effective strategy likely to improve the morbidity and mortality from pancreatic cancer would be the identification of accurate, noninvasive diagnostic markers that would enable earlier diagnosis of symptomatic patients and earlier detection of cancer in asymptomatic in...

Abstract Background Pancreatic serous cystadenoma (SCA) is a benign, cystic lesion with an indolent growth pattern. Complications such as spontaneous hemorrhage or malignant transformation from SCA are extremely rare. Our case report describes unusual presentation of patient previously diagnosed SCA, made unique by the presence three separate neoplasms in final specimen. Case A 74-year-old male...

Background: To retrospectively evaluate whether quantitative information derived from spectral imaging can improve the differential diagnosis of pancreatic cystic masses including pancreatic solid pseudopapillary epithelial neoplasms (SPENs), mucin- producing cysts and pseudocysts. Materials and Methods: From June 2015 to October 2017, 56 patients (22 pseudocysts, 18 mucin-producing cysts and 1...

Context Carcinoembryonic antigen analysis of pancreatic cyst fluid is the tumor marker of choice for preoperatively differentiating mucinous from non-mucinous cystic lesions. Objective We aim to determine the most accurate cyst carcinoembryonic antigen cut-off value for distinguishing mucinous cysts from non-mucinous cysts with a focus on discriminating intraductal papillary mucinous neoplasms....