iron overload is known to occur in the west european and american population due to the consumption of iron-rich diets. on the other hand, genetic disorders leading to iron overload are also known. iron overload leads to increased peroxidation and disruptive disintegration of lipid-rich membranes, and predisposes humans for an enhanced risk of cancer induction. in experimental animals iron over...

For deep CNN-based image classification models, we observe that confusions between classes with high visual similarity are much stronger than those where classes are visually dissimilar. With these unbalanced confusions, classes can be organized in communities, which is similar to cliques of people in the social network. Based on this, we propose a graph-based tool named “confusion graph” to qu...

Interaction on the Web is often problematic for visually disabled users. In order to analyse how visually disabled users deal with problematic situations we carried out a secondary analysis of 2 independent datasets containing the interaction of 24 users. As a result, we determine the situations in which coping occurs including uncertainty, reduced mobility, confusion and overload, and identify...

Focal, segmental, and diffuse liver pathologies have been described in the literature. This article describes a pattern in which liver pathology is confined to a lobe. This lobar pattern has not been described previously to our knowledge. Herein, we illustrate computed tomography (CT) and magnetic resonance imaging (MRI) findings of diffuse lobar involvement patterns in various ...

It has been proposed that modest levels of stored iron, far less than conventional iron overload, promote cardiovascular disease and that sustained iron depletion is protective against it.1– 6 This so-called “iron hypothesis” was initially presented as an explanation for the sex difference in cardiovascular disease and the increase in disease after menopause. The idea, although continually deba...

It has been proposed that modest levels of stored iron, far less than conventional iron overload, promote cardiovascular disease and that sustained iron depletion is protective against it.1– 6 This so-called “iron hypothesis” was initially presented as an explanation for the sex difference in cardiovascular disease and the increase in disease after menopause. The idea, although continually deba...