Background One of the most promising therapies in persistent and severe food allergy is oral immunotherapy (OIT), with immediate goal of desensitization and long-term goal of tolerance. However, a subgroup of patients may experience severe allergic reactions. These concerns might be addressed by combination of OIT with another promising therapy involving anti-IgE monoclonal antibodies (omalizum...

Background Food allergies have become more prevalent and long lasting over the past two decades, namely cow’s milk allergy (CMA). Standard management for this disease is based on allergen avoidance and symptomatic treatment of accidental allergic reactions. The possibility of obtaining oral desensitization in patients with food allergy is still a mater of debate but seems to be a promising spec...

Case report A fourteen-year old boy was referred to our clinic for follow-up with the diagnosis of cow’s milk allergy. At 3 months of age, he had immediate rash around his mouth and vomiting when he was first introduced with infant formula. Since then, he was on a milk restriction diet. He had three anaphylactic reactions needing emergency visit, and epinephrine injections. His last anaphylacti...

conclusions emdr is an effective tool for curing or decreasing the level of anxiety in myocardial patients. results the findings collected during the 12-month follow-up indicated that emdr was effective for treating anxiety in myocardial patients. materials and methods this study was a clinical trial study. sixty myocardial patients were selected using convenience random sampling and divided in...

Cross-reactivity of cashew and pistachio pecan walnut has been reported in the past. We hypothesized that oral immunotherapy (OIT) lead to desensitization, respectively. Chart review was done on patients who underwent or OIT using a previously published protocol at New England Food Allergy Treatment Center from 2014 2019. Following protocol, every patient offered challenge after reaching mainte...

BACKGROUND Peanut allergy is an increasingly common health problem. Current treatment guidelines are based on strict avoidance. However, in the last few years, oral immunotherapy protocols have shown promising results yielding increased tolerance to peanut in allergic children. Adolescence is particularly at risk. METHODS/DESIGN We have designed a randomized, double-blind, placebo-controlled,...

BACKGROUND The most suitable approach for patients with aspirin hypersensitivity undergoing percutaneous coronary intervention remains to be assessed. METHODS AND RESULTS Pubmed, Google Scholar, and Cochrane were systematically searched for papers describing protocols about aspirin hypersensitivity in the percutaneous coronary intervention setting. Discharge from hospital with aspirin was the...

Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...

The oral sensation elicited by carbonated water is reduced by capsaicin and by blockers of carbonic anhydrase. We have investigated the temporal profile of this sensation and its cross-desensitization by capsaicin. We additionally tested if the sensation is influenced by amiloride. Following pretreatment of half of the dorsal tongue with 33 p.p.m. capsaicin, carbonated water was flowed over the...