نتایج جستجو برای: onset diabetes of the young mody

تعداد نتایج: 22867488  

2009
Renata Lorini Catherine Klersy Giuseppe d'Annunzio Ornella Massa Nicola Minuto Dario Iafusco Christine Bellannè-Chantelot Anna Paola Frongia Sonia Toni Franco Meschi Franco Cerutti Fabrizio Barbetti

OBJECTIVE To investigate the prevalence of maturity-onset diabetes of the young (MODY) in Italian children with incidental hyperglycemia. RESEARCH DESIGN AND METHODS Among 748 subjects age 1-18 years with incidental hyperglycemia, minimal diagnostic criteria for MODY were met by 172 families. Mutational analyses of the glucokinase (GCK) and hepatocyte nuclear factor 1alpha (HNF1A) genes were ...

Journal: :Public health genomics 2015
Angeli M van der Zwaag Stephanie S Weinreich Astrid R Bosma Tessel Rigter Monique Losekoot Lidewij Henneman Martina C Cornel

AIMS Currently, many patients with maturity onset diabetes of the young (MODY) are undiagnosed or misdiagnosed with type 1 or 2 diabetes. This study aims to assess professional experts' views on factors which may influence the current practice of genetic testing for MODY and to explore next steps toward best practice. METHODS Twelve semistructured interviews were conducted with professional e...

Journal: :The Journal of clinical endocrinology and metabolism 2017
Liana K Billings Kathleen A Jablonski A Sofia Warner Yu-Chien Cheng Jarred B McAteer Laura Tipton Alan R Shuldiner David A Ehrmann Alisa K Manning Dana Dabelea Paul W Franks Steven E Kahn Toni I Pollin William C Knowler David Altshuler Jose C Florez

Context Variation in genes that cause maturity-onset diabetes of the young (MODY) has been associated with diabetes incidence and glycemic traits. Objectives This study aimed to determine whether genetic variation in MODY genes leads to differential responses to insulin-sensitizing interventions. Design and Setting This was a secondary analysis of a multicenter, randomized clinical trial, t...

Journal: :Internal medicine 1997
A Kadota-Shinozaki T Nakamura H Hidaka H Kojima H Yasuda A Kashiwagi R Kikkawa

A 19-year-old woman with diabetic lipemia and maturity-onset diabetes of the young (MODY) is reported. Though her insulin secretory activity was preserved, she fell into mild diabetic ketoacidosis (DKA) and showed type V hyperlipidemia. Post-heparin plasma activity of lipoprotein lipase (LPL) was decreased even 10 days after initiating insulin injection but not deficient. The abnormalities in l...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سمنان - دانشکده علوم انسانی 1393

charles dickens was a voracious reader even in his childhood. his early reading of seventeenth- and eighteenth-century picaresque fiction greatly influenced his writing style. his first novel, the pickwick papers, is a tale of rogues and swindlers, adventures and quests, satire and comedy, and innocence and experience. oliver twist, dickens’ second novel, is a young boy’s progress through a cor...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز 1390

the present research study attempted to find out the extent to which two pre-task activities of “glossary of unknown vocabulary items” and “content related support” assisted efl language learners with their performance on listening comprehension questions across two different proficiency levels (low and high). data for this study were obtained from a total of 120 language learners, female and m...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه گیلان - دانشکده علوم انسانی 1391

short story as an important literary genre in the recent decade is focused by many of young writers and literary critical with searching structure, content , artistic techniques and cognitive phenomenon of these works , we can show quantity of using some parts of storied literature from new literal techniques of the word and also we can show the usage of native, cultural and social foundation...

Journal: :Diabetes care 2014
Maurizio Delvecchio Ornella Ludovico Claudia Menzaghi Rosa Di Paola Leopoldo Zelante Antonella Marucci Valeria Grasso Vincenzo Trischitta Massimo Carella Fabrizio Barbetti Francesco Gallo Maria Susanna Coccioli Clara Zecchino Maria Felicia Faienza Giuliana Cardinale Adriana Franzese Enza Mozzillo Dario Iafusco Angela Zanfardino

Maturity-onset diabetes of the young (MODY; MIM# 606391) is a genetically and clinically heterogeneous form of diabetes, accounting for 1–2% of all diabetes cases (1). MODY is characterized by mild hyperglycemia or overt diabetes usually detected in three consecutive generations, with onset before the age of 25 years and absence of type 1 diabetes autoantibodies. Among the thirteen MODY genes i...

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